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• W2013097310 abstract "A series of tetrahydroisoquinolines acting as dual serotonin transporter inhibitor/histamine H(3) antagonists is described. The introduction of polar aromatic spacers as part of the histamine H(3) pharmacophore was explored. A convergent synthesis of the final products allowing late stage introduction of the aromatic side chain was developed. In vitro and in vivo data are discussed." @default.
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• W2013097310 date "2007-10-01" @default.
• W2013097310 modified "2023-10-11" @default.
• W2013097310 title "Dual serotonin transporter inhibitor/histamine H3 antagonists: Development of rigidified H3 pharmacophores" @default.
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• W2013097310 doi "https://doi.org/10.1016/j.bmcl.2007.08.017" @default.
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