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• W2013102922 endingPage "627" @default.
• W2013102922 startingPage "627" @default.
• W2013102922 abstract "To characterize the influence of diet-induced changes in body fat on colitis severity in SMAD3-/- mice.SMAD3-/- mice (6-8 wk of age) were randomly assigned to receive a calorie restricted (30% of control; CR), control (CON), or high fat (HF) diet for 20 wk and were gavaged with sterile broth or with Helicobacter hepaticus (H. hepaticus) to induce colitis. Four weeks after infection, mice were sacrificed and the cecum and colons were processed for histological evaluation.Dietary treatment significantly influenced body composition prior to infection (P < 0.05), with CR mice having less (14% ± 2%) and HF-fed mice more body fat (32% ± 7%) compared to controls (22% ± 4%). Differences in body composition were associated with alterations in plasma levels of leptin (HF > CON > CR) and adiponectin (CON > HF ≥ CR) (P < 0.05). There were no significant differences in colitis scores between CON and HF-fed mice 4 wk post-infection. Consistent with this, differences in proliferation and inflammation markers (COX-2, iNOS), and infiltrating cell types (CD3+ T lymphocytes, macrophages) were not observed. Unexpectedly, only 40% of CR mice survived infection with H. hepaticus, with mortality observed as early as 1 wk following induction of colitis.Increased adiposity does not influence colitis severity in SMAD3-/- mice. Importantly, caloric restriction negatively impacts survival following pathogen challenge, potentially due to an impaired immune response." @default.
• W2013102922 created "2016-06-24" @default.
• W2013102922 creator A5018510680 @default.
• W2013102922 date "2012-01-01" @default.
• W2013102922 modified "2023-09-23" @default.
• W2013102922 title "Differential effects of energy balance on experimentally-induced colitis" @default.
• W2013102922 cites W1523751054 @default.
• W2013102922 cites W1554123323 @default.
• W2013102922 cites W1575824899 @default.
• W2013102922 cites W1590709474 @default.
• W2013102922 cites W1965830486 @default.
• W2013102922 cites W1966132436 @default.
• W2013102922 cites W1971620656 @default.
• W2013102922 cites W1977791993 @default.
• W2013102922 cites W1979948289 @default.
• W2013102922 cites W1981261500 @default.
• W2013102922 cites W1981444005 @default.
• W2013102922 cites W1983674511 @default.
• W2013102922 cites W1984076434 @default.
• W2013102922 cites W1987444905 @default.
• W2013102922 cites W1988099321 @default.
• W2013102922 cites W1994961575 @default.
• W2013102922 cites W1995703529 @default.
• W2013102922 cites W1996713062 @default.
• W2013102922 cites W1998009398 @default.
• W2013102922 cites W2003828583 @default.
• W2013102922 cites W2012433024 @default.
• W2013102922 cites W2012652877 @default.
• W2013102922 cites W2013813550 @default.
• W2013102922 cites W2018757636 @default.
• W2013102922 cites W2025334057 @default.
• W2013102922 cites W2026324404 @default.
• W2013102922 cites W2027109870 @default.
• W2013102922 cites W2030046677 @default.
• W2013102922 cites W2038393880 @default.
• W2013102922 cites W2038576766 @default.
• W2013102922 cites W2038757260 @default.
• W2013102922 cites W2044798581 @default.
• W2013102922 cites W2045261990 @default.
• W2013102922 cites W2049677309 @default.
• W2013102922 cites W2049769977 @default.
• W2013102922 cites W2052435488 @default.
• W2013102922 cites W2053911884 @default.
• W2013102922 cites W2059652342 @default.
• W2013102922 cites W2061772512 @default.
• W2013102922 cites W2067104364 @default.
• W2013102922 cites W2073175436 @default.
• W2013102922 cites W2074627893 @default.
• W2013102922 cites W2078657772 @default.
• W2013102922 cites W2079584533 @default.
• W2013102922 cites W2085408028 @default.
• W2013102922 cites W2089560557 @default.
• W2013102922 cites W2091759162 @default.
• W2013102922 cites W2095083228 @default.
• W2013102922 cites W2095164057 @default.
• W2013102922 cites W2095900954 @default.
• W2013102922 cites W2096613981 @default.
• W2013102922 cites W2097270587 @default.
• W2013102922 cites W2098768454 @default.
• W2013102922 cites W2099317105 @default.
• W2013102922 cites W2101176748 @default.
• W2013102922 cites W2112884350 @default.
• W2013102922 cites W2116050875 @default.
• W2013102922 cites W2117760446 @default.
• W2013102922 cites W2118769722 @default.
• W2013102922 cites W2122300727 @default.
• W2013102922 cites W2124313822 @default.
• W2013102922 cites W2125840439 @default.
• W2013102922 cites W2130200649 @default.
• W2013102922 cites W2130764919 @default.
• W2013102922 cites W2130766522 @default.
• W2013102922 cites W2133662608 @default.
• W2013102922 cites W2133895102 @default.
• W2013102922 cites W2139671137 @default.
• W2013102922 cites W2146791717 @default.
• W2013102922 cites W2151987208 @default.
• W2013102922 cites W2152870115 @default.
• W2013102922 cites W2158208709 @default.
• W2013102922 cites W2165345254 @default.
• W2013102922 cites W2166370133 @default.
• W2013102922 cites W2166449272 @default.
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• W2013102922 doi "https://doi.org/10.3748/wjg.v18.i7.627" @default.
• W2013102922 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3281219" @default.
• W2013102922 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22363133" @default.
• W2013102922 hasPublicationYear "2012" @default.
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