Matches in SemOpenAlex for { <https://semopenalex.org/work/W2013112306> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2013112306 endingPage "229" @default.
- W2013112306 startingPage "225" @default.
- W2013112306 abstract "Evaluation of: Kwan WH, Navarro-Sanchez E, Dumortier H et al.: Dermal-type macrophage expressing CD209/DC-SIGN show inherent resistance to Dengue virus growth. PLoS Negl. Trop. Dis. 2(10), E311 (2008). Dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin (DC-SIGN/CD209) was recently identified as a molecule that facilitates Dengue virus entry, leading to productive cellular infection. Initially, DC-SIGN expression was thought to be restricted to dendritic cells, however, it is now known that tissue macrophages also express it. Here we review a paper that used an ex vivo and an in vitro model of skin-dwelling macrophages expressing DC-SIGN, demonstrating that they are nonproductively infected with the Dengue virus. The authors reveal a novel type I interferon-independent mechanism whereby the virus enters these DC-SIGN-bearing cells but traffics to poorly acidified phagosomes, thereby limiting viral replication. We discuss this new model to study early infection and local host defenses against viral replication using IL-10-derived dermal macrophages expressing DC-SIGN." @default.
- W2013112306 created "2016-06-24" @default.
- W2013112306 creator A5034983595 @default.
- W2013112306 creator A5089233990 @default.
- W2013112306 date "2009-05-01" @default.
- W2013112306 modified "2023-09-25" @default.
- W2013112306 title "Model for local skin defense against Dengue virus infection" @default.
- W2013112306 cites W1494401243 @default.
- W2013112306 cites W1566992315 @default.
- W2013112306 cites W171525608 @default.
- W2013112306 cites W1782561717 @default.
- W2013112306 cites W1927805758 @default.
- W2013112306 cites W1928251300 @default.
- W2013112306 cites W1987702283 @default.
- W2013112306 cites W2006619058 @default.
- W2013112306 cites W2017270296 @default.
- W2013112306 cites W2017583377 @default.
- W2013112306 cites W2034464954 @default.
- W2013112306 cites W2059095830 @default.
- W2013112306 cites W2062700377 @default.
- W2013112306 cites W2090973041 @default.
- W2013112306 cites W2100166387 @default.
- W2013112306 cites W2109204917 @default.
- W2013112306 cites W2116011139 @default.
- W2013112306 cites W2120446258 @default.
- W2013112306 cites W2129401286 @default.
- W2013112306 cites W2134717733 @default.
- W2013112306 cites W2151252156 @default.
- W2013112306 cites W2159086771 @default.
- W2013112306 cites W2160928682 @default.
- W2013112306 cites W2163812052 @default.
- W2013112306 cites W2411528578 @default.
- W2013112306 doi "https://doi.org/10.2217/fvl.09.6" @default.
- W2013112306 hasPublicationYear "2009" @default.
- W2013112306 type Work @default.
- W2013112306 sameAs 2013112306 @default.
- W2013112306 citedByCount "0" @default.
- W2013112306 crossrefType "journal-article" @default.
- W2013112306 hasAuthorship W2013112306A5034983595 @default.
- W2013112306 hasAuthorship W2013112306A5089233990 @default.
- W2013112306 hasConcept C140704245 @default.
- W2013112306 hasConcept C159047783 @default.
- W2013112306 hasConcept C193976658 @default.
- W2013112306 hasConcept C196594336 @default.
- W2013112306 hasConcept C202751555 @default.
- W2013112306 hasConcept C203014093 @default.
- W2013112306 hasConcept C2522874641 @default.
- W2013112306 hasConcept C26291073 @default.
- W2013112306 hasConcept C2776178377 @default.
- W2013112306 hasConcept C2778170410 @default.
- W2013112306 hasConcept C2779635636 @default.
- W2013112306 hasConcept C533803919 @default.
- W2013112306 hasConcept C54355233 @default.
- W2013112306 hasConcept C86803240 @default.
- W2013112306 hasConcept C8891405 @default.
- W2013112306 hasConcept C95444343 @default.
- W2013112306 hasConceptScore W2013112306C140704245 @default.
- W2013112306 hasConceptScore W2013112306C159047783 @default.
- W2013112306 hasConceptScore W2013112306C193976658 @default.
- W2013112306 hasConceptScore W2013112306C196594336 @default.
- W2013112306 hasConceptScore W2013112306C202751555 @default.
- W2013112306 hasConceptScore W2013112306C203014093 @default.
- W2013112306 hasConceptScore W2013112306C2522874641 @default.
- W2013112306 hasConceptScore W2013112306C26291073 @default.
- W2013112306 hasConceptScore W2013112306C2776178377 @default.
- W2013112306 hasConceptScore W2013112306C2778170410 @default.
- W2013112306 hasConceptScore W2013112306C2779635636 @default.
- W2013112306 hasConceptScore W2013112306C533803919 @default.
- W2013112306 hasConceptScore W2013112306C54355233 @default.
- W2013112306 hasConceptScore W2013112306C86803240 @default.
- W2013112306 hasConceptScore W2013112306C8891405 @default.
- W2013112306 hasConceptScore W2013112306C95444343 @default.
- W2013112306 hasIssue "3" @default.
- W2013112306 hasLocation W20131123061 @default.
- W2013112306 hasOpenAccess W2013112306 @default.
- W2013112306 hasPrimaryLocation W20131123061 @default.
- W2013112306 hasRelatedWork W1751219545 @default.
- W2013112306 hasRelatedWork W2034125106 @default.
- W2013112306 hasRelatedWork W2076100628 @default.
- W2013112306 hasRelatedWork W2096105915 @default.
- W2013112306 hasRelatedWork W2100364502 @default.
- W2013112306 hasRelatedWork W2108939276 @default.
- W2013112306 hasRelatedWork W2124479668 @default.
- W2013112306 hasRelatedWork W2521741667 @default.
- W2013112306 hasRelatedWork W2569060603 @default.
- W2013112306 hasRelatedWork W3204874602 @default.
- W2013112306 hasVolume "4" @default.
- W2013112306 isParatext "false" @default.
- W2013112306 isRetracted "false" @default.
- W2013112306 magId "2013112306" @default.
- W2013112306 workType "article" @default.