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- W2013115599 abstract "Mouse mammary carcinoma mutant cell line FUA169, characterized by high GM3 ganglioside content, was established from parent cell line FM3A/F28-7, which has high LacCer content but no GM3. Although both cell lines showed the same quantity and quality of integrin receptors, FUA169 showed much stronger adhesion to fibronectin (FN)-coated plates than did F28-7. Liposomes containing phosphatidylcholine, cholesterol, alpha 5 beta 1, and a moderate amount of GM3 showed greatly enhanced adhesion to FN-coated plates, but adhesion of similar liposomes containing a large amount of GM3, or no GM3, was much lower. Our results suggest that GM3 regulates integrin receptor function essential for cell adhesion to FN." @default.
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- W2013115599 date "1992-08-01" @default.
- W2013115599 modified "2023-09-26" @default.
- W2013115599 title "Regulatory role of GM3 ganglioside in integrin function, as evidenced by its effect on function of α5β1-liposomes: A preliminary note" @default.
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- W2013115599 doi "https://doi.org/10.1016/s0006-291x(05)81561-x" @default.
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