Matches in SemOpenAlex for { <https://semopenalex.org/work/W2013116810> ?p ?o ?g. }
- W2013116810 endingPage "359" @default.
- W2013116810 startingPage "353" @default.
- W2013116810 abstract "Diabetes is accompanied by lipid abnormalities, which contribute significantly to cardiovascular morbidity and mortality in diabetic patients. We previously demonstrated the potent antihyperglycemic activity of the active principle (fraction II from Sephadex LH 20 chromatography [LH II]) isolated from ethanolic seed extract of Eugenia jambolana in diabetic rabbits. In the present study, the efficacy of LH II was evaluated for its hypolipidemic activity in alloxan-induced mildly diabetic (MD) and severely diabetic (SD) rabbits. Phytochemical investigation of LH II by various structural spectra showed the presence of saturated fatty acid, Δ(5) lipid, and sterol. Oral administration of LH II (10 mg/kg of body weight) for 21 days resulted in improved glycemic control in both MD and SD rabbits. After treatment with LH II, serum total cholesterol, triglycerides, high-density lipoprotein cholesterol, and the total cholesterol/high-density lipoprotein cholesterol ratio were significantly improved. LH II also resulted in significant (P < .001) improvement in 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity and levels of total lipids and glycogen in both MD and SD rabbits. Thus, the present study demonstrates that LH II possesses potent hypolipidemic activity and efficacy in both MD and SD rabbits." @default.
- W2013116810 created "2016-06-24" @default.
- W2013116810 creator A5010086504 @default.
- W2013116810 creator A5043679934 @default.
- W2013116810 creator A5076233885 @default.
- W2013116810 creator A5085239274 @default.
- W2013116810 date "2011-04-01" @default.
- W2013116810 modified "2023-09-27" @default.
- W2013116810 title "Antihyperlipidemic Effect of Active Principle Isolated from Seed of<i>Eugenia jambolana</i>on Alloxan-Induced Diabetic Rabbits" @default.
- W2013116810 cites W1898641180 @default.
- W2013116810 cites W1946263363 @default.
- W2013116810 cites W1968489152 @default.
- W2013116810 cites W1988719208 @default.
- W2013116810 cites W1988983679 @default.
- W2013116810 cites W1998683247 @default.
- W2013116810 cites W2001255601 @default.
- W2013116810 cites W2006693847 @default.
- W2013116810 cites W2014759828 @default.
- W2013116810 cites W2022417334 @default.
- W2013116810 cites W2023286233 @default.
- W2013116810 cites W2040255703 @default.
- W2013116810 cites W2048767498 @default.
- W2013116810 cites W2071298657 @default.
- W2013116810 cites W2072629310 @default.
- W2013116810 cites W2075001753 @default.
- W2013116810 cites W2080370880 @default.
- W2013116810 cites W2084306238 @default.
- W2013116810 cites W2123167115 @default.
- W2013116810 cites W2137798279 @default.
- W2013116810 cites W2149300470 @default.
- W2013116810 cites W2150898264 @default.
- W2013116810 cites W2154774609 @default.
- W2013116810 cites W2162884669 @default.
- W2013116810 cites W2218787476 @default.
- W2013116810 cites W2323529898 @default.
- W2013116810 cites W2341665659 @default.
- W2013116810 doi "https://doi.org/10.1089/jmf.2010.1227" @default.
- W2013116810 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21370965" @default.
- W2013116810 hasPublicationYear "2011" @default.
- W2013116810 type Work @default.
- W2013116810 sameAs 2013116810 @default.
- W2013116810 citedByCount "22" @default.
- W2013116810 countsByYear W20131168102012 @default.
- W2013116810 countsByYear W20131168102013 @default.
- W2013116810 countsByYear W20131168102014 @default.
- W2013116810 countsByYear W20131168102015 @default.
- W2013116810 countsByYear W20131168102016 @default.
- W2013116810 countsByYear W20131168102017 @default.
- W2013116810 countsByYear W20131168102018 @default.
- W2013116810 countsByYear W20131168102020 @default.
- W2013116810 countsByYear W20131168102021 @default.
- W2013116810 countsByYear W20131168102022 @default.
- W2013116810 crossrefType "journal-article" @default.
- W2013116810 hasAuthorship W2013116810A5010086504 @default.
- W2013116810 hasAuthorship W2013116810A5043679934 @default.
- W2013116810 hasAuthorship W2013116810A5076233885 @default.
- W2013116810 hasAuthorship W2013116810A5085239274 @default.
- W2013116810 hasConcept C126322002 @default.
- W2013116810 hasConcept C134018914 @default.
- W2013116810 hasConcept C134651460 @default.
- W2013116810 hasConcept C163994747 @default.
- W2013116810 hasConcept C181199279 @default.
- W2013116810 hasConcept C185592680 @default.
- W2013116810 hasConcept C195475562 @default.
- W2013116810 hasConcept C2777499176 @default.
- W2013116810 hasConcept C2778163477 @default.
- W2013116810 hasConcept C2779123261 @default.
- W2013116810 hasConcept C2780072125 @default.
- W2013116810 hasConcept C2780473172 @default.
- W2013116810 hasConcept C2781005915 @default.
- W2013116810 hasConcept C55493867 @default.
- W2013116810 hasConcept C555293320 @default.
- W2013116810 hasConcept C71924100 @default.
- W2013116810 hasConcept C8243546 @default.
- W2013116810 hasConceptScore W2013116810C126322002 @default.
- W2013116810 hasConceptScore W2013116810C134018914 @default.
- W2013116810 hasConceptScore W2013116810C134651460 @default.
- W2013116810 hasConceptScore W2013116810C163994747 @default.
- W2013116810 hasConceptScore W2013116810C181199279 @default.
- W2013116810 hasConceptScore W2013116810C185592680 @default.
- W2013116810 hasConceptScore W2013116810C195475562 @default.
- W2013116810 hasConceptScore W2013116810C2777499176 @default.
- W2013116810 hasConceptScore W2013116810C2778163477 @default.
- W2013116810 hasConceptScore W2013116810C2779123261 @default.
- W2013116810 hasConceptScore W2013116810C2780072125 @default.
- W2013116810 hasConceptScore W2013116810C2780473172 @default.
- W2013116810 hasConceptScore W2013116810C2781005915 @default.
- W2013116810 hasConceptScore W2013116810C55493867 @default.
- W2013116810 hasConceptScore W2013116810C555293320 @default.
- W2013116810 hasConceptScore W2013116810C71924100 @default.
- W2013116810 hasConceptScore W2013116810C8243546 @default.
- W2013116810 hasIssue "4" @default.
- W2013116810 hasLocation W20131168101 @default.
- W2013116810 hasLocation W20131168102 @default.
- W2013116810 hasOpenAccess W2013116810 @default.
- W2013116810 hasPrimaryLocation W20131168101 @default.
- W2013116810 hasRelatedWork W1969856370 @default.
- W2013116810 hasRelatedWork W1972925419 @default.