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- W2013119669 abstract "The in-vitro activity of two combinations of sulbactam and cefoperazone against 187 strains of Bacteroides fragilis were evaluated; their activity was compared with that of the drugs alone, and correlated with the production of beta-lactamase by the bacterial strains. The results indicated that both combinations had a synergistic effect: the addition of 8 mg/l of sulbactam to the MIC of cefoperazone reduced the percentage of resistant strains from 58% to 0.5%; while the combination of two parts of cefoperazone to one pact of sulbactam lowered the resistance rate to 1%. Synergy was observed most frequently with beta-lactamase positive strains, but it also occurred among beta-lactamase negative strains." @default.
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- W2013119669 date "1986-01-01" @default.
- W2013119669 modified "2023-09-26" @default.
- W2013119669 title "In-vitro activity of cefoperazone-sulbactam against Bacteroides species" @default.
- W2013119669 doi "https://doi.org/10.1093/jac/18.4.467" @default.
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