FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2013123119> ?p ?o ?g. }

• W2013123119 endingPage "1159" @default.
• W2013123119 startingPage "1157" @default.
• W2013123119 abstract "Over 50 years ago, a deadly autoimmune disease known as pernicious anemia, which is characterized by neurological and hematological abnormalities, had no known cure. The isolation of the anti-pernicious anemia factor from liver extracts by Folkers and Smith in 1948 represented a breakthrough in the treatment of this disease (21, 25). Named vitamin B12, this compound could be isolated as pure, red crystals from various animal and microbial sources, and the X-ray crystal structure of this complex molecule, one of the largest nonpolymeric natural compounds, was determined in the 1950s by Dorothy Hodgkin et al. (Fig. ​(Fig.1A)1A) (8). Since that time, thousands of researchers have identified and characterized a variety of enzymes that utilize B12 cofactors, determined the complex pathway for B12 absorption in humans, and elucidated the microbial pathways for B12 biosynthesis. Other forms of vitamin B12 have been found in nature, but their functions are not fully understood. In this issue of the Journal of Bacteriology, Anderson et al. provide evidence that a form of B12 known as “pseudo-B12” (Fig. ​(Fig.1B)1B) is a physiologically important form of B12 in Salmonella enterica serovar Typhimurium (1).FIG. 1.Corrinoids produced by S. enterica. Cobalamin (A) and pseudo-B12 (B) differ in their α-axial ligands. The β-axial ligand (R) is 5′-deoxyadenosine or -CH3 in B12 cofactors and -CN in vitamin B12. Collectively, these molecules are ...Unlike all other vitamins, vitamin B12 is not produced by plants; rather, its biosynthesis is restricted to certain prokaryotes (23). Animals obtain B12 from food or, in some cases, directly from resident B12-producing microbes (28). S. enterica has long been used as a model organism for studying B12 biosynthesis (23)." @default.
• W2013123119 created "2016-06-24" @default.
• W2013123119 creator A5031848177 @default.
• W2013123119 creator A5090953868 @default.
• W2013123119 date "2008-02-15" @default.
• W2013123119 modified "2023-09-23" @default.
• W2013123119 title "Pseudo-B ₁₂ Joins the Cofactor Family" @default.
• W2013123119 cites W1482270815 @default.
• W2013123119 cites W1977111421 @default.
• W2013123119 cites W1979946184 @default.
• W2013123119 cites W1986091806 @default.
• W2013123119 cites W2001876970 @default.
• W2013123119 cites W2002788904 @default.
• W2013123119 cites W2025897722 @default.
• W2013123119 cites W2040520672 @default.
• W2013123119 cites W2042317540 @default.
• W2013123119 cites W2044106520 @default.
• W2013123119 cites W2044136800 @default.
• W2013123119 cites W2050173547 @default.
• W2013123119 cites W2054183278 @default.
• W2013123119 cites W2054482694 @default.
• W2013123119 cites W2059247897 @default.
• W2013123119 cites W2063983897 @default.
• W2013123119 cites W2067841828 @default.
• W2013123119 cites W2078238095 @default.
• W2013123119 cites W2082053892 @default.
• W2013123119 cites W2105537674 @default.
• W2013123119 cites W2110615030 @default.
• W2013123119 cites W2123628854 @default.
• W2013123119 cites W2130326089 @default.
• W2013123119 cites W2138694962 @default.
• W2013123119 cites W2158282653 @default.
• W2013123119 cites W2163432198 @default.
• W2013123119 cites W2164418156 @default.
• W2013123119 cites W2308752893 @default.
• W2013123119 cites W2887195480 @default.
• W2013123119 doi "https://doi.org/10.1128/jb.01892-07" @default.
• W2013123119 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2238202" @default.
• W2013123119 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18083805" @default.
• W2013123119 hasPublicationYear "2008" @default.
• W2013123119 type Work @default.
• W2013123119 sameAs 2013123119 @default.
• W2013123119 citedByCount "24" @default.
• W2013123119 countsByYear W20131231192012 @default.
• W2013123119 countsByYear W20131231192013 @default.
• W2013123119 countsByYear W20131231192014 @default.
• W2013123119 countsByYear W20131231192015 @default.
• W2013123119 countsByYear W20131231192016 @default.
• W2013123119 countsByYear W20131231192017 @default.
• W2013123119 countsByYear W20131231192018 @default.
• W2013123119 countsByYear W20131231192019 @default.
• W2013123119 countsByYear W20131231192020 @default.
• W2013123119 countsByYear W20131231192022 @default.
• W2013123119 crossrefType "journal-article" @default.
• W2013123119 hasAuthorship W2013123119A5031848177 @default.
• W2013123119 hasAuthorship W2013123119A5090953868 @default.
• W2013123119 hasBestOaLocation W20131231191 @default.
• W2013123119 hasConcept C181199279 @default.
• W2013123119 hasConcept C197957613 @default.
• W2013123119 hasConcept C199360897 @default.
• W2013123119 hasConcept C2778692605 @default.
• W2013123119 hasConcept C2908821069 @default.
• W2013123119 hasConcept C2993175405 @default.
• W2013123119 hasConcept C41008148 @default.
• W2013123119 hasConcept C523546767 @default.
• W2013123119 hasConcept C54355233 @default.
• W2013123119 hasConcept C55493867 @default.
• W2013123119 hasConcept C86803240 @default.
• W2013123119 hasConceptScore W2013123119C181199279 @default.
• W2013123119 hasConceptScore W2013123119C197957613 @default.
• W2013123119 hasConceptScore W2013123119C199360897 @default.
• W2013123119 hasConceptScore W2013123119C2778692605 @default.
• W2013123119 hasConceptScore W2013123119C2908821069 @default.
• W2013123119 hasConceptScore W2013123119C2993175405 @default.
• W2013123119 hasConceptScore W2013123119C41008148 @default.
• W2013123119 hasConceptScore W2013123119C523546767 @default.
• W2013123119 hasConceptScore W2013123119C54355233 @default.
• W2013123119 hasConceptScore W2013123119C55493867 @default.
• W2013123119 hasConceptScore W2013123119C86803240 @default.
• W2013123119 hasIssue "4" @default.
• W2013123119 hasLocation W20131231191 @default.
• W2013123119 hasLocation W20131231192 @default.
• W2013123119 hasLocation W20131231193 @default.
• W2013123119 hasLocation W20131231194 @default.
• W2013123119 hasOpenAccess W2013123119 @default.
• W2013123119 hasPrimaryLocation W20131231191 @default.
• W2013123119 hasRelatedWork W1920751942 @default.
• W2013123119 hasRelatedWork W1975356393 @default.
• W2013123119 hasRelatedWork W1991523530 @default.
• W2013123119 hasRelatedWork W2002128513 @default.
• W2013123119 hasRelatedWork W2013123119 @default.
• W2013123119 hasRelatedWork W2020824267 @default.
• W2013123119 hasRelatedWork W2031436818 @default.
• W2013123119 hasRelatedWork W2057739827 @default.
• W2013123119 hasRelatedWork W2075354549 @default.
• W2013123119 hasRelatedWork W2092874662 @default.
• W2013123119 hasVolume "190" @default.
• W2013123119 isParatext "false" @default.

• next