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• W2013128596 abstract "• IL-36 family cytokines share 20–52% homology with IL-1Ra. • N-terminal processing is required for optimal bioactivity of IL-36 cytokines. • IL-36 modulates immune responses by DC activation and T helper subset polarization. • IL-36 signaling plays a crucial role in skin homeostasis and inflammation. IL-36α, IL-36β, IL-36γ, and IL-36Ra, collectively called IL-36 cytokines, are part of the IL-1 family. IL-36α, IL-36β, and IL-36γ are IL-36 receptor (IL-36R) agonists, while IL-36Ra is a receptor antagonist that blocks the activation of IL-36R signaling. IL-36 cytokines require processing in order to become fully active, however the protease(s) responsible for this are currently not known. The IL-36 receptor pathway activates dendritic cells and plays a role in polarizing T-helper responses. The skin is the predominant site where IL-36 cytokines are expressed and several reports have established that they play a significant role in the pathogenesis of skin diseases. In this review the discovery and biological function of the cytokines IL-36α, IL-36β, IL-36γ and IL-36Ra will be discussed, and their role in the pathogenesis of a wide variety of diseases." @default.
• W2013128596 created "2016-06-24" @default.
• W2013128596 creator A5013338602 @default.
• W2013128596 creator A5074759534 @default.
• W2013128596 date "2013-12-01" @default.
• W2013128596 modified "2023-10-17" @default.
• W2013128596 title "Biology of IL-36 cytokines and their role in disease" @default.
• W2013128596 cites W1545027309 @default.
• W2013128596 cites W1800668800 @default.
• W2013128596 cites W1903523261 @default.
• W2013128596 cites W1965170225 @default.
• W2013128596 cites W1970278160 @default.
• W2013128596 cites W1973924724 @default.
• W2013128596 cites W1975184461 @default.
• W2013128596 cites W1976602505 @default.
• W2013128596 cites W1978423918 @default.
• W2013128596 cites W1982444180 @default.
• W2013128596 cites W1985410925 @default.
• W2013128596 cites W1986477351 @default.
• W2013128596 cites W1988999016 @default.
• W2013128596 cites W1989418853 @default.
• W2013128596 cites W1999807078 @default.
• W2013128596 cites W2005043395 @default.
• W2013128596 cites W2005503891 @default.
• W2013128596 cites W2017689331 @default.
• W2013128596 cites W2019645050 @default.
• W2013128596 cites W2028141281 @default.
• W2013128596 cites W2031745594 @default.
• W2013128596 cites W2039722030 @default.
• W2013128596 cites W2045015441 @default.
• W2013128596 cites W2051771323 @default.
• W2013128596 cites W2052943307 @default.
• W2013128596 cites W2053941041 @default.
• W2013128596 cites W2054985203 @default.
• W2013128596 cites W2062291274 @default.
• W2013128596 cites W2064676254 @default.
• W2013128596 cites W2064876782 @default.
• W2013128596 cites W2067591914 @default.
• W2013128596 cites W2067791830 @default.
• W2013128596 cites W2075039399 @default.
• W2013128596 cites W2076052954 @default.
• W2013128596 cites W2078625967 @default.
• W2013128596 cites W2086423366 @default.
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• W2013128596 cites W2097504851 @default.
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• W2013128596 cites W2099578672 @default.
• W2013128596 cites W2100151241 @default.
• W2013128596 cites W2115234798 @default.
• W2013128596 cites W2115807849 @default.
• W2013128596 cites W2132394005 @default.
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• W2013128596 doi "https://doi.org/10.1016/j.smim.2013.11.003" @default.
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