Matches in SemOpenAlex for { <https://semopenalex.org/work/W2013137896> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2013137896 abstract "Though extrapulmonary small cell carcinoma was first described over 80 years ago, definitive treatment recommendations are lacking. The treatment strategies commonly utilized are extrapolated from pulmonary small cell carcinoma experience. A better understanding of this entity is needed to improve management approach. The University of Kansas tumor registry was reviewed from 1990 to 2013. Thirty-five cases met the inclusion and exclusion criteria for review. Age, gender, smoking status, weight loss, metastatic disease-related data, stage, performance status (PS), treatment received, and survival data were collected. Patients were evaluated with a variety of primary locations of disease including GI tract (29%), GU tract (35%), Gyn organs (17%), head and neck (14%), and unknown primary (9%). Several sites of metastatic disease were noted, with 57 and 43% of patients meeting criteria for limited disease (LD) and extensive disease (ED), respectively. Chemotherapy, surgery, and radiation were used in several different regimens, with small cell lung cancer-type regimens incorporating a platinum and etoposide being the most common (74%). Patients with LD had a median survival of 36 months compared with 5 months in patients with ED (p<0.0001). Among different primary sites, patients with GU and Gyn LD tumors had best median survival of 36 months. Among other variables that were examined with respect to their poor prognostic significance, PS>2 (p=0.001) and one or fewer number of treatment modalities especially in LD (p=0.0005) were found to be associated significantly with mortality. GI and GU tract tumors were the most common primary sites of disease in our retrospective review. Survival varied according to stage, PS, site of primary disease, use of chemotherapy, and number of treatment modalities used. Further studies are needed to better understand this rare disorder and optimize management approach." @default.
- W2013137896 created "2016-06-24" @default.
- W2013137896 creator A5015345962 @default.
- W2013137896 creator A5025900183 @default.
- W2013137896 creator A5031433465 @default.
- W2013137896 creator A5035683534 @default.
- W2013137896 creator A5044916391 @default.
- W2013137896 date "2014-08-24" @default.
- W2013137896 modified "2023-10-03" @default.
- W2013137896 title "Extrapulmonary small cell carcinoma: the University of Kansas experience and review of literature" @default.
- W2013137896 cites W1956598055 @default.
- W2013137896 cites W1988063893 @default.
- W2013137896 cites W1988595500 @default.
- W2013137896 cites W1990612073 @default.
- W2013137896 cites W1992928214 @default.
- W2013137896 cites W2002682545 @default.
- W2013137896 cites W2011761477 @default.
- W2013137896 cites W2031828041 @default.
- W2013137896 cites W2042814020 @default.
- W2013137896 cites W2094268378 @default.
- W2013137896 cites W2102464609 @default.
- W2013137896 cites W2149519864 @default.
- W2013137896 cites W2285420222 @default.
- W2013137896 cites W2341745217 @default.
- W2013137896 cites W2395016922 @default.
- W2013137896 doi "https://doi.org/10.1007/s12032-014-0187-1" @default.
- W2013137896 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4248605" @default.
- W2013137896 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25151532" @default.
- W2013137896 hasPublicationYear "2014" @default.
- W2013137896 type Work @default.
- W2013137896 sameAs 2013137896 @default.
- W2013137896 citedByCount "21" @default.
- W2013137896 countsByYear W20131378962015 @default.
- W2013137896 countsByYear W20131378962016 @default.
- W2013137896 countsByYear W20131378962017 @default.
- W2013137896 countsByYear W20131378962018 @default.
- W2013137896 countsByYear W20131378962019 @default.
- W2013137896 countsByYear W20131378962020 @default.
- W2013137896 countsByYear W20131378962021 @default.
- W2013137896 countsByYear W20131378962022 @default.
- W2013137896 crossrefType "journal-article" @default.
- W2013137896 hasAuthorship W2013137896A5015345962 @default.
- W2013137896 hasAuthorship W2013137896A5025900183 @default.
- W2013137896 hasAuthorship W2013137896A5031433465 @default.
- W2013137896 hasAuthorship W2013137896A5035683534 @default.
- W2013137896 hasAuthorship W2013137896A5044916391 @default.
- W2013137896 hasBestOaLocation W20131378962 @default.
- W2013137896 hasConcept C121608353 @default.
- W2013137896 hasConcept C126322002 @default.
- W2013137896 hasConcept C141071460 @default.
- W2013137896 hasConcept C143998085 @default.
- W2013137896 hasConcept C2776694085 @default.
- W2013137896 hasConcept C2776907518 @default.
- W2013137896 hasConcept C2777546739 @default.
- W2013137896 hasConcept C2778119113 @default.
- W2013137896 hasConcept C2779134260 @default.
- W2013137896 hasConcept C2779292878 @default.
- W2013137896 hasConcept C509974204 @default.
- W2013137896 hasConcept C71924100 @default.
- W2013137896 hasConceptScore W2013137896C121608353 @default.
- W2013137896 hasConceptScore W2013137896C126322002 @default.
- W2013137896 hasConceptScore W2013137896C141071460 @default.
- W2013137896 hasConceptScore W2013137896C143998085 @default.
- W2013137896 hasConceptScore W2013137896C2776694085 @default.
- W2013137896 hasConceptScore W2013137896C2776907518 @default.
- W2013137896 hasConceptScore W2013137896C2777546739 @default.
- W2013137896 hasConceptScore W2013137896C2778119113 @default.
- W2013137896 hasConceptScore W2013137896C2779134260 @default.
- W2013137896 hasConceptScore W2013137896C2779292878 @default.
- W2013137896 hasConceptScore W2013137896C509974204 @default.
- W2013137896 hasConceptScore W2013137896C71924100 @default.
- W2013137896 hasIssue "10" @default.
- W2013137896 hasLocation W20131378961 @default.
- W2013137896 hasLocation W20131378962 @default.
- W2013137896 hasLocation W20131378963 @default.
- W2013137896 hasLocation W20131378964 @default.
- W2013137896 hasOpenAccess W2013137896 @default.
- W2013137896 hasPrimaryLocation W20131378961 @default.
- W2013137896 hasRelatedWork W1582240157 @default.
- W2013137896 hasRelatedWork W1966706097 @default.
- W2013137896 hasRelatedWork W2029688276 @default.
- W2013137896 hasRelatedWork W2082691227 @default.
- W2013137896 hasRelatedWork W2089643552 @default.
- W2013137896 hasRelatedWork W2339333593 @default.
- W2013137896 hasRelatedWork W2348495938 @default.
- W2013137896 hasRelatedWork W2389384568 @default.
- W2013137896 hasRelatedWork W2404042595 @default.
- W2013137896 hasRelatedWork W3029964572 @default.
- W2013137896 hasVolume "31" @default.
- W2013137896 isParatext "false" @default.
- W2013137896 isRetracted "false" @default.
- W2013137896 magId "2013137896" @default.
- W2013137896 workType "article" @default.