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- W2013183896 abstract "<h3>Abstract</h3> Coalescent-based species tree inference has become widely used in the analysis of genome-scale multilocus and SNP datasets when the goal is inference of a species-level phylogeny. However, numerous evolutionary processes are known to violate the assumptions of a coalescence-only model and complicate inference of the species tree. One such process is hybrid speciation, in which a species shares its ancestry with two distinct species. Although many methods have been proposed to detect hybrid speciation, only a few have considered both hybridization and coalescence in a unified framework, and these are generally limited to the setting in which putative hybrid species must be identified in advance. Here we propose a method that can examine genome-scale data for a large number of taxa and detect those taxa that may have arisen via hybridization, as well as their potential “parental” taxa. The method is based on a model that considers both coalescence and hybridization together, and uses phylogenetic invariants to construct a test that scales well in terms of computational time for both the number of taxa and the amount of sequence data. We test the method using simulated data for up 20 taxa and 100,000bp, and find that the method accurately identifies both recent and ancient hybrid species in less than 30 seconds. We apply the method to two empirical datasets, one composed of <i>Sistrurus</i> rattlesnakes for which hybrid speciation is not supported by previous work, and one consisting of several species of <i>Heliconius</i> butterflies for which some evidence of hybrid speciation has been previously found." @default.
- W2013183896 created "2016-06-24" @default.
- W2013183896 creator A5019298601 @default.
- W2013183896 date "1943-07-03" @default.
- W2013183896 modified "2023-09-27" @default.
- W2013183896 title "Refresher Courses for Service M.O.s" @default.
- W2013183896 doi "https://doi.org/10.1136/bmj.2.4304.19-a" @default.
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