FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2013189552> ?p ?o ?g. }

• W2013189552 endingPage "1833" @default.
• W2013189552 startingPage "1828" @default.
• W2013189552 abstract "Study objectives The basic premise of CT screening is that size is an important determinant of survival in lung cancer. We sought to examine this hypothesis within stage IA non-small cell lung cancer (NSCLC). Methods A retrospective analysis of all patients with pathologically confirmed stage IA NSCLC resected from 1991 to 2001 was conducted. All but seven patients underwent anatomic lung resection and mediastinal lymph node dissection. Kaplan-Meier survival analysis was performed to estimate the 5-year overall and disease-specific survival probability stratified by tumor size. The influence of age, gender, histology, and tumor size on survival was also analyzed using a Cox proportional hazards regression model. Results There were 244 patients (mean age, 66.7 years; 45.1% were men). Lobectomy was performed in 229 patients, segmentectomy in 8 patients, and wedge resection in 7 patients. Operative mortality was 0.4%. Histologic breakdown was as follows: adenocarcinoma (59.4%), squamous (18.9%), bronchoalveolar (15.2%), large cell (4.5%), and poorly differentiated (2.0%). The median follow-up time for all patients was 2.6 years. The 5-year survival probability for all patients was 71.1% (95% confidence interval [CI], 63.6 to 78.6%). For 161 patients with tumor sizes ≤ 2.0 cm, the 5-year survival probability was 77.2% (95% CI, 68.6 to 85.8%) in comparison with 60.3% (95% CI, 46.7 to 73.8%) in 83 patients with tumor size > 2.0 cm (p = 0.03 by log-rank test). The overall 5-year disease-specific survival was 74.9% (95% CI, 67.6 to 82.2%). Disease-specific survival was 81.4% (95% CI, 73.3 to 89.4%) for patients with tumors ≤ 2.0 cm and 63.4% (95% CI, 49.6 to 77.1%) for patients with tumors > 2.0 cm. Conclusions These data suggest that size within stage IA is an important predictor of survival and that further substaging should be considered. The basic premise of CT screening is that size is an important determinant of survival in lung cancer. We sought to examine this hypothesis within stage IA non-small cell lung cancer (NSCLC). A retrospective analysis of all patients with pathologically confirmed stage IA NSCLC resected from 1991 to 2001 was conducted. All but seven patients underwent anatomic lung resection and mediastinal lymph node dissection. Kaplan-Meier survival analysis was performed to estimate the 5-year overall and disease-specific survival probability stratified by tumor size. The influence of age, gender, histology, and tumor size on survival was also analyzed using a Cox proportional hazards regression model. There were 244 patients (mean age, 66.7 years; 45.1% were men). Lobectomy was performed in 229 patients, segmentectomy in 8 patients, and wedge resection in 7 patients. Operative mortality was 0.4%. Histologic breakdown was as follows: adenocarcinoma (59.4%), squamous (18.9%), bronchoalveolar (15.2%), large cell (4.5%), and poorly differentiated (2.0%). The median follow-up time for all patients was 2.6 years. The 5-year survival probability for all patients was 71.1% (95% confidence interval [CI], 63.6 to 78.6%). For 161 patients with tumor sizes ≤ 2.0 cm, the 5-year survival probability was 77.2% (95% CI, 68.6 to 85.8%) in comparison with 60.3% (95% CI, 46.7 to 73.8%) in 83 patients with tumor size > 2.0 cm (p = 0.03 by log-rank test). The overall 5-year disease-specific survival was 74.9% (95% CI, 67.6 to 82.2%). Disease-specific survival was 81.4% (95% CI, 73.3 to 89.4%) for patients with tumors ≤ 2.0 cm and 63.4% (95% CI, 49.6 to 77.1%) for patients with tumors > 2.0 cm. These data suggest that size within stage IA is an important predictor of survival and that further substaging should be considered." @default.
• W2013189552 created "2016-06-24" @default.
• W2013189552 creator A5004921008 @default.
• W2013189552 creator A5012652944 @default.
• W2013189552 creator A5035601705 @default.
• W2013189552 creator A5043186678 @default.
• W2013189552 creator A5053267529 @default.
• W2013189552 creator A5084396616 @default.
• W2013189552 date "2003-11-01" @default.
• W2013189552 modified "2023-10-14" @default.
• W2013189552 title "Tumor Size Predicts Survival Within Stage IA Non-Small Cell Lung Cancer *" @default.
• W2013189552 cites W2023840681 @default.
• W2013189552 cites W2031827337 @default.
• W2013189552 cites W2037350927 @default.
• W2013189552 cites W2082429274 @default.
• W2013189552 cites W2082576197 @default.
• W2013189552 cites W2087065324 @default.
• W2013189552 cites W2087981692 @default.
• W2013189552 cites W2116567054 @default.
• W2013189552 cites W2122833820 @default.
• W2013189552 cites W2123927174 @default.
• W2013189552 cites W2135247698 @default.
• W2013189552 cites W2886176140 @default.
• W2013189552 doi "https://doi.org/10.1378/chest.124.5.1828" @default.
• W2013189552 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14605056" @default.
• W2013189552 hasPublicationYear "2003" @default.
• W2013189552 type Work @default.
• W2013189552 sameAs 2013189552 @default.
• W2013189552 citedByCount "151" @default.
• W2013189552 countsByYear W20131895522012 @default.
• W2013189552 countsByYear W20131895522013 @default.
• W2013189552 countsByYear W20131895522014 @default.
• W2013189552 countsByYear W20131895522015 @default.
• W2013189552 countsByYear W20131895522016 @default.
• W2013189552 countsByYear W20131895522017 @default.
• W2013189552 countsByYear W20131895522018 @default.
• W2013189552 countsByYear W20131895522019 @default.
• W2013189552 countsByYear W20131895522020 @default.
• W2013189552 countsByYear W20131895522021 @default.
• W2013189552 countsByYear W20131895522022 @default.
• W2013189552 countsByYear W20131895522023 @default.
• W2013189552 crossrefType "journal-article" @default.
• W2013189552 hasAuthorship W2013189552A5004921008 @default.
• W2013189552 hasAuthorship W2013189552A5012652944 @default.
• W2013189552 hasAuthorship W2013189552A5035601705 @default.
• W2013189552 hasAuthorship W2013189552A5043186678 @default.
• W2013189552 hasAuthorship W2013189552A5053267529 @default.
• W2013189552 hasAuthorship W2013189552A5084396616 @default.
• W2013189552 hasConcept C10515644 @default.
• W2013189552 hasConcept C121608353 @default.
• W2013189552 hasConcept C126322002 @default.
• W2013189552 hasConcept C141071460 @default.
• W2013189552 hasConcept C146357865 @default.
• W2013189552 hasConcept C151730666 @default.
• W2013189552 hasConcept C159110652 @default.
• W2013189552 hasConcept C2776053289 @default.
• W2013189552 hasConcept C2776256026 @default.
• W2013189552 hasConcept C2776283816 @default.
• W2013189552 hasConcept C2779013556 @default.
• W2013189552 hasConcept C2780379385 @default.
• W2013189552 hasConcept C2780849966 @default.
• W2013189552 hasConcept C2781182431 @default.
• W2013189552 hasConcept C44249647 @default.
• W2013189552 hasConcept C50382708 @default.
• W2013189552 hasConcept C66339696 @default.
• W2013189552 hasConcept C71924100 @default.
• W2013189552 hasConcept C86803240 @default.
• W2013189552 hasConceptScore W2013189552C10515644 @default.
• W2013189552 hasConceptScore W2013189552C121608353 @default.
• W2013189552 hasConceptScore W2013189552C126322002 @default.
• W2013189552 hasConceptScore W2013189552C141071460 @default.
• W2013189552 hasConceptScore W2013189552C146357865 @default.
• W2013189552 hasConceptScore W2013189552C151730666 @default.
• W2013189552 hasConceptScore W2013189552C159110652 @default.
• W2013189552 hasConceptScore W2013189552C2776053289 @default.
• W2013189552 hasConceptScore W2013189552C2776256026 @default.
• W2013189552 hasConceptScore W2013189552C2776283816 @default.
• W2013189552 hasConceptScore W2013189552C2779013556 @default.
• W2013189552 hasConceptScore W2013189552C2780379385 @default.
• W2013189552 hasConceptScore W2013189552C2780849966 @default.
• W2013189552 hasConceptScore W2013189552C2781182431 @default.
• W2013189552 hasConceptScore W2013189552C44249647 @default.
• W2013189552 hasConceptScore W2013189552C50382708 @default.
• W2013189552 hasConceptScore W2013189552C66339696 @default.
• W2013189552 hasConceptScore W2013189552C71924100 @default.
• W2013189552 hasConceptScore W2013189552C86803240 @default.
• W2013189552 hasIssue "5" @default.
• W2013189552 hasLocation W20131895521 @default.
• W2013189552 hasLocation W20131895522 @default.
• W2013189552 hasOpenAccess W2013189552 @default.
• W2013189552 hasPrimaryLocation W20131895521 @default.
• W2013189552 hasRelatedWork W2166883766 @default.
• W2013189552 hasRelatedWork W2210807927 @default.
• W2013189552 hasRelatedWork W2364092196 @default.
• W2013189552 hasRelatedWork W2569474543 @default.
• W2013189552 hasRelatedWork W3030888969 @default.
• W2013189552 hasRelatedWork W3065452909 @default.
• W2013189552 hasRelatedWork W3171502986 @default.

• next