Matches in SemOpenAlex for { <https://semopenalex.org/work/W2013201067> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2013201067 abstract "Sialorrhea can have major negative effects on the physical and social well-being. Sclerotherapy may be useful in patients with sialorrhea by decreasing the amount of saliva production. The aim of this study was to test the effect of ethanolamine oleate (EO) in an experimental model as a preliminary step for its application in humans.Histopathological and morphometric analysis of submandibular glands from thirteen dogs was preformed. A total of 25 glands were injected with 1ml of 2.5% EO (n=5), 1ml of 5% EO (n=5), 5ml of 2.5% EO (n=5) and 5ml of 5% EO (n=5). Five glands were used as control.EO significantly induced a dose dependent scaring of the gland ending in lobular transformation (salivary gland cirrhosis). Morphometric measurements showed that 1ml of 2.5% or 5% EO significantly induced fibrosis compared to normal glands (p=0.014 and 0.021, respectively). Fibrosis significantly increased and was more apparent when a dose of 5ml of 2.5% EO or 5% EO were injected [by semi-quantitative evaluation (p=0.016 and 0.002, respectively) and morphometric measurements (p=0.016 and 0.008, respectively)]. This scarring effect was significantly associated with reduction of area of acinar cells when a dose of 1ml-5%, 5ml-2.5% or 5ml-5% EO were applied (p=0.03. 0.012 and 0.004, respectively). Moreover, ductal injury was only significant when a dose of 5ml of 5% EO was used (p=0.034). This dose and concentration (i.e. 5ml-5% EO) had a significant synergetic effect [p=0.0119].In this model, treatment with EO proved to permanently reduce the acinar area through induction of progressive, irreversible and dose dependant scarring (medical sialoadenectomy)." @default.
- W2013201067 created "2016-06-24" @default.
- W2013201067 creator A5024328641 @default.
- W2013201067 creator A5026297135 @default.
- W2013201067 creator A5038832060 @default.
- W2013201067 creator A5049871609 @default.
- W2013201067 date "2013-03-01" @default.
- W2013201067 modified "2023-09-27" @default.
- W2013201067 title "Evaluation of ethanolamine oleate sclerotherapy on the submandibular glands of canines as a potential therapy for sialorrhea" @default.
- W2013201067 cites W152477735 @default.
- W2013201067 cites W1582652007 @default.
- W2013201067 cites W194630416 @default.
- W2013201067 cites W1963536094 @default.
- W2013201067 cites W1968931311 @default.
- W2013201067 cites W1987734299 @default.
- W2013201067 cites W1989254251 @default.
- W2013201067 cites W1990948226 @default.
- W2013201067 cites W1991994280 @default.
- W2013201067 cites W1993829552 @default.
- W2013201067 cites W1999424768 @default.
- W2013201067 cites W2013068641 @default.
- W2013201067 cites W2018223333 @default.
- W2013201067 cites W2054980493 @default.
- W2013201067 cites W2081682569 @default.
- W2013201067 cites W2093205280 @default.
- W2013201067 cites W2110078851 @default.
- W2013201067 cites W2116973424 @default.
- W2013201067 cites W2121911584 @default.
- W2013201067 cites W2162036908 @default.
- W2013201067 cites W2412095785 @default.
- W2013201067 doi "https://doi.org/10.1016/j.ijporl.2012.11.024" @default.
- W2013201067 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23246419" @default.
- W2013201067 hasPublicationYear "2013" @default.
- W2013201067 type Work @default.
- W2013201067 sameAs 2013201067 @default.
- W2013201067 citedByCount "4" @default.
- W2013201067 countsByYear W20132010672017 @default.
- W2013201067 countsByYear W20132010672018 @default.
- W2013201067 countsByYear W20132010672020 @default.
- W2013201067 crossrefType "journal-article" @default.
- W2013201067 hasAuthorship W2013201067A5024328641 @default.
- W2013201067 hasAuthorship W2013201067A5026297135 @default.
- W2013201067 hasAuthorship W2013201067A5038832060 @default.
- W2013201067 hasAuthorship W2013201067A5049871609 @default.
- W2013201067 hasConcept C126322002 @default.
- W2013201067 hasConcept C134018914 @default.
- W2013201067 hasConcept C141071460 @default.
- W2013201067 hasConcept C142724271 @default.
- W2013201067 hasConcept C2778230777 @default.
- W2013201067 hasConcept C2778937882 @default.
- W2013201067 hasConcept C2780266248 @default.
- W2013201067 hasConcept C2780559512 @default.
- W2013201067 hasConcept C2909146933 @default.
- W2013201067 hasConcept C504460877 @default.
- W2013201067 hasConcept C71924100 @default.
- W2013201067 hasConcept C90924648 @default.
- W2013201067 hasConceptScore W2013201067C126322002 @default.
- W2013201067 hasConceptScore W2013201067C134018914 @default.
- W2013201067 hasConceptScore W2013201067C141071460 @default.
- W2013201067 hasConceptScore W2013201067C142724271 @default.
- W2013201067 hasConceptScore W2013201067C2778230777 @default.
- W2013201067 hasConceptScore W2013201067C2778937882 @default.
- W2013201067 hasConceptScore W2013201067C2780266248 @default.
- W2013201067 hasConceptScore W2013201067C2780559512 @default.
- W2013201067 hasConceptScore W2013201067C2909146933 @default.
- W2013201067 hasConceptScore W2013201067C504460877 @default.
- W2013201067 hasConceptScore W2013201067C71924100 @default.
- W2013201067 hasConceptScore W2013201067C90924648 @default.
- W2013201067 hasLocation W20132010671 @default.
- W2013201067 hasLocation W20132010672 @default.
- W2013201067 hasOpenAccess W2013201067 @default.
- W2013201067 hasPrimaryLocation W20132010671 @default.
- W2013201067 hasRelatedWork W2013201067 @default.
- W2013201067 hasRelatedWork W2021560856 @default.
- W2013201067 hasRelatedWork W2044826694 @default.
- W2013201067 hasRelatedWork W2045653827 @default.
- W2013201067 hasRelatedWork W2052174593 @default.
- W2013201067 hasRelatedWork W2058424427 @default.
- W2013201067 hasRelatedWork W2108156506 @default.
- W2013201067 hasRelatedWork W2135784605 @default.
- W2013201067 hasRelatedWork W2143682524 @default.
- W2013201067 hasRelatedWork W4233477339 @default.
- W2013201067 isParatext "false" @default.
- W2013201067 isRetracted "false" @default.
- W2013201067 magId "2013201067" @default.
- W2013201067 workType "article" @default.