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- W2013204455 abstract "The translocator protein (TSPO) is an 18 kDa transmembrane protein primarily found in the outer mitochondrial membrane where it forms a key part of the mitochondrial permeability transition pore (MPTP). Omnipresent in almost all tissues, TSPO up-regulation has been connected to neuronal damage and inflammation, making the protein an important bio-imaging marker for disease progression. More recently, TSPO has attracted attention as a possible molecular target for tumour imaging and chemotherapy. In this review we summarize TSPO's molecular characteristics and highlight research progress in recent years in the field of TSPO-targeted cancer diagnostics and treatments." @default.
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- W2013204455 date "1988-04-01" @default.
- W2013204455 modified "2023-10-03" @default.
- W2013204455 title "Dramatic increase in peripheral benzodiazepine binding sites in human colonic adenocarcinoma as compared to normal colon" @default.
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- W2013204455 doi "https://doi.org/10.1016/0014-2999(88)90135-5" @default.
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