FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2013214548> ?p ?o ?g. }

• W2013214548 endingPage "397" @default.
• W2013214548 startingPage "389" @default.
• W2013214548 abstract "We investigated the toxicity of aggregated nanoparticles of cerium oxide (CeO2) using an in vitro 3D human bronchial epithelial model that included a mucociliary apparatus (MucilAir™). CeO2 was dispersed in saline and applied to the apical surface of the model. CeO2 did not induce distinct effects in the model, whereas it did in BEAS-2B and A549 cell cultures. The absence of effects of CeO2 was not because of the model’s insensitivity. Nanoparticles of zinc oxide (ZnO) elicited positive responses in the toxicological assays. Respiratory mucus (0.1% and 1%) added to dispersions increased aggregation/agglomeration to such an extent that most CeO2 sedimented within a few minutes. Also, the mucociliary apparatus of the model removed CeO2 from the central part of the apical surface to the borders. This ‘clearance’ may have prevented the majority of CeO2 from reaching the epithelial cells. Chemical analysis of cerium in the basal tissue culture medium showed only minimal translocation of cerium across the 3D barrier. In conclusion, mucociliary defence appeared to prevent CeO2 reaching the respiratory epithelial cells in this 3D in vitro model. This model and approach can be used to study compounds of specific toxicological concern in airway defence mechanisms in vitro." @default.
• W2013214548 created "2016-06-24" @default.
• W2013214548 creator A5011798735 @default.
• W2013214548 creator A5033929384 @default.
• W2013214548 creator A5035603269 @default.
• W2013214548 creator A5043878934 @default.
• W2013214548 creator A5060470365 @default.
• W2013214548 creator A5065332769 @default.
• W2013214548 creator A5077729944 @default.
• W2013214548 creator A5081174471 @default.
• W2013214548 creator A5083087820 @default.
• W2013214548 creator A5084989697 @default.
• W2013214548 date "2015-03-01" @default.
• W2013214548 modified "2023-10-18" @default.
• W2013214548 title "Toxicity assessment of aggregated/agglomerated cerium oxide nanoparticles in an in vitro 3D airway model: The influence of mucociliary clearance" @default.
• W2013214548 cites W1624483887 @default.
• W2013214548 cites W1965269308 @default.
• W2013214548 cites W1989447703 @default.
• W2013214548 cites W2003739102 @default.
• W2013214548 cites W2006933992 @default.
• W2013214548 cites W2011176452 @default.
• W2013214548 cites W2025188006 @default.
• W2013214548 cites W2042977409 @default.
• W2013214548 cites W2055215713 @default.
• W2013214548 cites W2062352064 @default.
• W2013214548 cites W2070320427 @default.
• W2013214548 cites W2081172377 @default.
• W2013214548 cites W2083108532 @default.
• W2013214548 cites W2087468617 @default.
• W2013214548 cites W2091474030 @default.
• W2013214548 cites W2096458399 @default.
• W2013214548 cites W2125760551 @default.
• W2013214548 cites W2126948841 @default.
• W2013214548 cites W2145333524 @default.
• W2013214548 cites W2153584068 @default.
• W2013214548 cites W2155118487 @default.
• W2013214548 cites W2159502819 @default.
• W2013214548 cites W2326211379 @default.
• W2013214548 cites W2419098194 @default.
• W2013214548 cites W4246349309 @default.
• W2013214548 doi "https://doi.org/10.1016/j.tiv.2014.10.017" @default.
• W2013214548 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25448805" @default.
• W2013214548 hasPublicationYear "2015" @default.
• W2013214548 type Work @default.
• W2013214548 sameAs 2013214548 @default.
• W2013214548 citedByCount "50" @default.
• W2013214548 countsByYear W20132145482015 @default.
• W2013214548 countsByYear W20132145482016 @default.
• W2013214548 countsByYear W20132145482017 @default.
• W2013214548 countsByYear W20132145482018 @default.
• W2013214548 countsByYear W20132145482019 @default.
• W2013214548 countsByYear W20132145482020 @default.
• W2013214548 countsByYear W20132145482021 @default.
• W2013214548 countsByYear W20132145482022 @default.
• W2013214548 countsByYear W20132145482023 @default.
• W2013214548 crossrefType "journal-article" @default.
• W2013214548 hasAuthorship W2013214548A5011798735 @default.
• W2013214548 hasAuthorship W2013214548A5033929384 @default.
• W2013214548 hasAuthorship W2013214548A5035603269 @default.
• W2013214548 hasAuthorship W2013214548A5043878934 @default.
• W2013214548 hasAuthorship W2013214548A5060470365 @default.
• W2013214548 hasAuthorship W2013214548A5065332769 @default.
• W2013214548 hasAuthorship W2013214548A5077729944 @default.
• W2013214548 hasAuthorship W2013214548A5081174471 @default.
• W2013214548 hasAuthorship W2013214548A5083087820 @default.
• W2013214548 hasAuthorship W2013214548A5084989697 @default.
• W2013214548 hasConcept C114682108 @default.
• W2013214548 hasConcept C12554922 @default.
• W2013214548 hasConcept C126322002 @default.
• W2013214548 hasConcept C127445965 @default.
• W2013214548 hasConcept C155672457 @default.
• W2013214548 hasConcept C171250308 @default.
• W2013214548 hasConcept C178790620 @default.
• W2013214548 hasConcept C185592680 @default.
• W2013214548 hasConcept C18903297 @default.
• W2013214548 hasConcept C192562407 @default.
• W2013214548 hasConcept C202751555 @default.
• W2013214548 hasConcept C2777312293 @default.
• W2013214548 hasConcept C2777714996 @default.
• W2013214548 hasConcept C2779851234 @default.
• W2013214548 hasConcept C2780657402 @default.
• W2013214548 hasConcept C29730261 @default.
• W2013214548 hasConcept C55493867 @default.
• W2013214548 hasConcept C71924100 @default.
• W2013214548 hasConcept C86803240 @default.
• W2013214548 hasConcept C95444343 @default.
• W2013214548 hasConcept C98274493 @default.
• W2013214548 hasConceptScore W2013214548C114682108 @default.
• W2013214548 hasConceptScore W2013214548C12554922 @default.
• W2013214548 hasConceptScore W2013214548C126322002 @default.
• W2013214548 hasConceptScore W2013214548C127445965 @default.
• W2013214548 hasConceptScore W2013214548C155672457 @default.
• W2013214548 hasConceptScore W2013214548C171250308 @default.
• W2013214548 hasConceptScore W2013214548C178790620 @default.
• W2013214548 hasConceptScore W2013214548C185592680 @default.
• W2013214548 hasConceptScore W2013214548C18903297 @default.
• W2013214548 hasConceptScore W2013214548C192562407 @default.
• W2013214548 hasConceptScore W2013214548C202751555 @default.

• next