Matches in SemOpenAlex for { <https://semopenalex.org/work/W2013224779> ?p ?o ?g. }
- W2013224779 endingPage "28" @default.
- W2013224779 startingPage "23" @default.
- W2013224779 abstract "Natural killer (NK) cells have been implied in the resistance against certain tumors and virally-infected cells. The prognostic significance of tumor infiltrating NK cells in primary squamous cell lung carcinoma (SqCLC) has not been fully studied. Fifty patients with primary SqCLC were evaluated for the presence of tumor infiltrating natural killer cells subset CD57 (TINK) after surgery. None of them received adjuvant therapy. Immunohistochemical studies of surgery pieces were performed by using the monoclonal antibody CD57. The number of TINK cells was counted by using a MICRON image analyzer. The total area studied for each tumor was of 1 cm(2). In this area, 50 intratumoral fields of 0.173 mm(2) were selected. The reference value used was the median (five TINK cells/field) of all tumors analyzed. After a minimum follow-up of 2 years the Kaplan-Meier method was used to obtain survival curves. Multivariate analysis were performed by using the Cox regression model. The survival was significantly better in patients with more than five TINK cells/field (Logrank P=0.0317). According to TNM classification, in those patients screened as stage IB (37 patients) the differences in survival were significantly higher (Logrank P=0.0016). In the multivariate analysis including TNM (surgical-pathologic stage), age, and endoscopy localization, the risk of death in patients with less than five TINK cells/field was 2.50 fold higher (CI 95%; range 1.07-5.85) than in those patients with more than five TINK cells/field. These results show that TINK cells appear to be a prognostic factor in the survival of patients with SqCLC. The possible antitumoral role of these cells in SqCLC is discussed." @default.
- W2013224779 created "2016-06-24" @default.
- W2013224779 creator A5000528518 @default.
- W2013224779 creator A5002763751 @default.
- W2013224779 creator A5010597765 @default.
- W2013224779 creator A5029442586 @default.
- W2013224779 creator A5050449284 @default.
- W2013224779 creator A5057582973 @default.
- W2013224779 creator A5069542925 @default.
- W2013224779 creator A5079846706 @default.
- W2013224779 date "2002-01-01" @default.
- W2013224779 modified "2023-10-10" @default.
- W2013224779 title "Prognostic significance of tumor infiltrating natural killer cells subset CD57 in patients with squamous cell lung cancer" @default.
- W2013224779 cites W1479728809 @default.
- W2013224779 cites W1534916753 @default.
- W2013224779 cites W1598996496 @default.
- W2013224779 cites W1643485318 @default.
- W2013224779 cites W1748261727 @default.
- W2013224779 cites W1922974839 @default.
- W2013224779 cites W1963939177 @default.
- W2013224779 cites W1968206976 @default.
- W2013224779 cites W1972680649 @default.
- W2013224779 cites W1980474076 @default.
- W2013224779 cites W1981444463 @default.
- W2013224779 cites W1981851073 @default.
- W2013224779 cites W1993312546 @default.
- W2013224779 cites W1995529916 @default.
- W2013224779 cites W2012358273 @default.
- W2013224779 cites W2014773767 @default.
- W2013224779 cites W2015217125 @default.
- W2013224779 cites W2016439741 @default.
- W2013224779 cites W2020153990 @default.
- W2013224779 cites W2038773326 @default.
- W2013224779 cites W2044813527 @default.
- W2013224779 cites W2047668722 @default.
- W2013224779 cites W2052175020 @default.
- W2013224779 cites W2053577376 @default.
- W2013224779 cites W2055770667 @default.
- W2013224779 cites W2066505103 @default.
- W2013224779 cites W2084336731 @default.
- W2013224779 cites W2093636317 @default.
- W2013224779 cites W2095368700 @default.
- W2013224779 cites W2099019634 @default.
- W2013224779 cites W2108614682 @default.
- W2013224779 cites W2110893132 @default.
- W2013224779 cites W2117900421 @default.
- W2013224779 cites W2132507383 @default.
- W2013224779 cites W2148222272 @default.
- W2013224779 cites W2153437241 @default.
- W2013224779 cites W2161937951 @default.
- W2013224779 cites W2327721037 @default.
- W2013224779 cites W4247919341 @default.
- W2013224779 doi "https://doi.org/10.1016/s0169-5002(01)00292-6" @default.
- W2013224779 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11750709" @default.
- W2013224779 hasPublicationYear "2002" @default.
- W2013224779 type Work @default.
- W2013224779 sameAs 2013224779 @default.
- W2013224779 citedByCount "372" @default.
- W2013224779 countsByYear W20132247792012 @default.
- W2013224779 countsByYear W20132247792013 @default.
- W2013224779 countsByYear W20132247792014 @default.
- W2013224779 countsByYear W20132247792015 @default.
- W2013224779 countsByYear W20132247792016 @default.
- W2013224779 countsByYear W20132247792017 @default.
- W2013224779 countsByYear W20132247792018 @default.
- W2013224779 countsByYear W20132247792019 @default.
- W2013224779 countsByYear W20132247792020 @default.
- W2013224779 countsByYear W20132247792021 @default.
- W2013224779 countsByYear W20132247792022 @default.
- W2013224779 countsByYear W20132247792023 @default.
- W2013224779 crossrefType "journal-article" @default.
- W2013224779 hasAuthorship W2013224779A5000528518 @default.
- W2013224779 hasAuthorship W2013224779A5002763751 @default.
- W2013224779 hasAuthorship W2013224779A5010597765 @default.
- W2013224779 hasAuthorship W2013224779A5029442586 @default.
- W2013224779 hasAuthorship W2013224779A5050449284 @default.
- W2013224779 hasAuthorship W2013224779A5057582973 @default.
- W2013224779 hasAuthorship W2013224779A5069542925 @default.
- W2013224779 hasAuthorship W2013224779A5079846706 @default.
- W2013224779 hasConcept C10515644 @default.
- W2013224779 hasConcept C109316439 @default.
- W2013224779 hasConcept C126322002 @default.
- W2013224779 hasConcept C142724271 @default.
- W2013224779 hasConcept C143998085 @default.
- W2013224779 hasConcept C146357865 @default.
- W2013224779 hasConcept C151730666 @default.
- W2013224779 hasConcept C202751555 @default.
- W2013224779 hasConcept C204232928 @default.
- W2013224779 hasConcept C2776256026 @default.
- W2013224779 hasConcept C2778102761 @default.
- W2013224779 hasConcept C50382708 @default.
- W2013224779 hasConcept C55493867 @default.
- W2013224779 hasConcept C66339696 @default.
- W2013224779 hasConcept C71924100 @default.
- W2013224779 hasConcept C86803240 @default.
- W2013224779 hasConceptScore W2013224779C10515644 @default.
- W2013224779 hasConceptScore W2013224779C109316439 @default.
- W2013224779 hasConceptScore W2013224779C126322002 @default.