Matches in SemOpenAlex for { <https://semopenalex.org/work/W2013228083> ?p ?o ?g. }
- W2013228083 abstract "Temperamental traits, the most basic part of personality, have been largely correlated with neurotransmitter systems and are under genetic control. Among serotonin candidates, the 2A receptor (5-HT(2A)) received considerable attention. We analyzed four SNPs (rs643627, rs594242, rs6311 and rs6313) in the 5-HT(2A) gene and their association with personality traits, as measured with the Temperament and Character Inventory (TCI). The sample was composed of three sub-groups: two German sub-samples, consisting of a healthy group of 289 subjects (42.6% males, mean age: 45.2+/-14.9) and a psychiatric patient group of 111 suicide attempters (38.7% males, mean age: 39.2+/-13.6), and an Italian sub-sample, composed of 60 mood disorder patients (35.0% males, mean age: 44.0+/-14.8). Controlling for sex, age and educational level, the SNPs were not strongly associated with personality dimensions. Only the rs594242 showed an association with Self-Directedness (p=0.003) in the German sample, while rs6313 was marginally associated with Novelty Seeking (p=0.01) in the Italian sample. We conclude that 5-HT(2A) SNPs may marginally modulate personality traits but further studies are required." @default.
- W2013228083 created "2016-06-24" @default.
- W2013228083 creator A5003149352 @default.
- W2013228083 creator A5015992288 @default.
- W2013228083 creator A5028714279 @default.
- W2013228083 creator A5042404471 @default.
- W2013228083 creator A5043595820 @default.
- W2013228083 creator A5054418565 @default.
- W2013228083 creator A5062596209 @default.
- W2013228083 date "2007-08-01" @default.
- W2013228083 modified "2023-09-27" @default.
- W2013228083 title "5-HT2A SNPs and the Temperament and Character Inventory" @default.
- W2013228083 cites W1964194614 @default.
- W2013228083 cites W1973475326 @default.
- W2013228083 cites W1974002816 @default.
- W2013228083 cites W1980671644 @default.
- W2013228083 cites W1984802541 @default.
- W2013228083 cites W1988306858 @default.
- W2013228083 cites W1988659527 @default.
- W2013228083 cites W1989639206 @default.
- W2013228083 cites W1991189774 @default.
- W2013228083 cites W1993854956 @default.
- W2013228083 cites W1995930538 @default.
- W2013228083 cites W1996455672 @default.
- W2013228083 cites W1999029753 @default.
- W2013228083 cites W1999325027 @default.
- W2013228083 cites W1999459029 @default.
- W2013228083 cites W2007375386 @default.
- W2013228083 cites W2011373732 @default.
- W2013228083 cites W2019692562 @default.
- W2013228083 cites W2029546955 @default.
- W2013228083 cites W2042028075 @default.
- W2013228083 cites W2043634812 @default.
- W2013228083 cites W2043732377 @default.
- W2013228083 cites W2044461300 @default.
- W2013228083 cites W2046038926 @default.
- W2013228083 cites W2047056305 @default.
- W2013228083 cites W2050763807 @default.
- W2013228083 cites W2052988008 @default.
- W2013228083 cites W2054179546 @default.
- W2013228083 cites W2055277208 @default.
- W2013228083 cites W2060181859 @default.
- W2013228083 cites W2060734129 @default.
- W2013228083 cites W2063473805 @default.
- W2013228083 cites W2074251394 @default.
- W2013228083 cites W2074404972 @default.
- W2013228083 cites W2078434036 @default.
- W2013228083 cites W2082313085 @default.
- W2013228083 cites W2083026893 @default.
- W2013228083 cites W2084965184 @default.
- W2013228083 cites W2091141407 @default.
- W2013228083 cites W2110564885 @default.
- W2013228083 cites W2112944975 @default.
- W2013228083 cites W2136222333 @default.
- W2013228083 cites W2137176353 @default.
- W2013228083 cites W2159103071 @default.
- W2013228083 cites W2162530578 @default.
- W2013228083 cites W2162969812 @default.
- W2013228083 cites W2164643746 @default.
- W2013228083 cites W2329975502 @default.
- W2013228083 cites W2415393834 @default.
- W2013228083 cites W2605054939 @default.
- W2013228083 cites W4211150788 @default.
- W2013228083 cites W4234565373 @default.
- W2013228083 doi "https://doi.org/10.1016/j.pnpbp.2007.05.008" @default.
- W2013228083 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17590256" @default.
- W2013228083 hasPublicationYear "2007" @default.
- W2013228083 type Work @default.
- W2013228083 sameAs 2013228083 @default.
- W2013228083 citedByCount "32" @default.
- W2013228083 countsByYear W20132280832012 @default.
- W2013228083 countsByYear W20132280832013 @default.
- W2013228083 countsByYear W20132280832014 @default.
- W2013228083 countsByYear W20132280832015 @default.
- W2013228083 countsByYear W20132280832016 @default.
- W2013228083 countsByYear W20132280832017 @default.
- W2013228083 crossrefType "journal-article" @default.
- W2013228083 hasAuthorship W2013228083A5003149352 @default.
- W2013228083 hasAuthorship W2013228083A5015992288 @default.
- W2013228083 hasAuthorship W2013228083A5028714279 @default.
- W2013228083 hasAuthorship W2013228083A5042404471 @default.
- W2013228083 hasAuthorship W2013228083A5043595820 @default.
- W2013228083 hasAuthorship W2013228083A5054418565 @default.
- W2013228083 hasAuthorship W2013228083A5062596209 @default.
- W2013228083 hasConcept C104317684 @default.
- W2013228083 hasConcept C135763542 @default.
- W2013228083 hasConcept C142853389 @default.
- W2013228083 hasConcept C153209595 @default.
- W2013228083 hasConcept C15744967 @default.
- W2013228083 hasConcept C179184181 @default.
- W2013228083 hasConcept C187288502 @default.
- W2013228083 hasConcept C2776529864 @default.
- W2013228083 hasConcept C2776582870 @default.
- W2013228083 hasConcept C2778699373 @default.
- W2013228083 hasConcept C2780733359 @default.
- W2013228083 hasConcept C2781293773 @default.
- W2013228083 hasConcept C2865642 @default.
- W2013228083 hasConcept C2992963524 @default.
- W2013228083 hasConcept C542102704 @default.
- W2013228083 hasConcept C54355233 @default.