FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2013243372> ?p ?o ?g. }

• W2013243372 endingPage "100" @default.
• W2013243372 startingPage "95" @default.
• W2013243372 abstract "The prion diseases or transmissible spongiform encephalopathy, such as human Creutzfeldt-Jakob disease (CJD) and so-called mad cow disease, are attributed to the causative agent, the scrapie variant of prion protein (PrP(Sc)) which causes fatal neurodegeneration. To investigate if stresses such as nitric oxide (NO) induced the cellular isoform of prion protein (PrP(C)), lipopolysaccharide, and sodium nitroprusside were used to treat N2a and NT2 cells, which resulted in elevated levels of the PRNP mRNA and prion protein. The signaling pathway for the NO-induced PrP(C) production involved guanylyl cyclase, MEK, and p38 MAPK as shown by the effect of specific pharmacological inhibitors ODQ, PD98059, and SB203580, respectively. Knowing the PrP induction by the biologically existing stimulus, this study provides useful information about the possible cellular mechanism and strategies for the treatment of CJD." @default.
• W2013243372 created "2016-06-24" @default.
• W2013243372 creator A5019968600 @default.
• W2013243372 creator A5022631782 @default.
• W2013243372 creator A5044128281 @default.
• W2013243372 creator A5071867905 @default.
• W2013243372 creator A5072138515 @default.
• W2013243372 date "2005-07-01" @default.
• W2013243372 modified "2023-09-24" @default.
• W2013243372 title "Nitric oxide induces prion protein via MEK and p38 MAPK signaling" @default.
• W2013243372 cites W1504283291 @default.
• W2013243372 cites W1965483182 @default.
• W2013243372 cites W1968689881 @default.
• W2013243372 cites W1972409470 @default.
• W2013243372 cites W1974130627 @default.
• W2013243372 cites W1978217169 @default.
• W2013243372 cites W1978283620 @default.
• W2013243372 cites W1980680117 @default.
• W2013243372 cites W1984445417 @default.
• W2013243372 cites W1985227130 @default.
• W2013243372 cites W1988861392 @default.
• W2013243372 cites W1995227965 @default.
• W2013243372 cites W1996299253 @default.
• W2013243372 cites W1997196023 @default.
• W2013243372 cites W2000966016 @default.
• W2013243372 cites W2007093034 @default.
• W2013243372 cites W2008748288 @default.
• W2013243372 cites W2010745676 @default.
• W2013243372 cites W2013679718 @default.
• W2013243372 cites W2020830047 @default.
• W2013243372 cites W2038887966 @default.
• W2013243372 cites W2048633023 @default.
• W2013243372 cites W2057293794 @default.
• W2013243372 cites W2062161568 @default.
• W2013243372 cites W2066604274 @default.
• W2013243372 cites W2074707482 @default.
• W2013243372 cites W2080981899 @default.
• W2013243372 cites W2086469326 @default.
• W2013243372 cites W2092220530 @default.
• W2013243372 cites W2118832299 @default.
• W2013243372 cites W2133538960 @default.
• W2013243372 cites W2151000339 @default.
• W2013243372 cites W2151400960 @default.
• W2013243372 cites W2318017958 @default.
• W2013243372 cites W2396275106 @default.
• W2013243372 doi "https://doi.org/10.1016/j.bbrc.2005.05.091" @default.
• W2013243372 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15936714" @default.
• W2013243372 hasPublicationYear "2005" @default.
• W2013243372 type Work @default.
• W2013243372 sameAs 2013243372 @default.
• W2013243372 citedByCount "20" @default.
• W2013243372 countsByYear W20132433722012 @default.
• W2013243372 countsByYear W20132433722013 @default.
• W2013243372 countsByYear W20132433722014 @default.
• W2013243372 countsByYear W20132433722017 @default.
• W2013243372 countsByYear W20132433722020 @default.
• W2013243372 countsByYear W20132433722022 @default.
• W2013243372 countsByYear W20132433722023 @default.
• W2013243372 crossrefType "journal-article" @default.
• W2013243372 hasAuthorship W2013243372A5019968600 @default.
• W2013243372 hasAuthorship W2013243372A5022631782 @default.
• W2013243372 hasAuthorship W2013243372A5044128281 @default.
• W2013243372 hasAuthorship W2013243372A5071867905 @default.
• W2013243372 hasAuthorship W2013243372A5072138515 @default.
• W2013243372 hasConcept C104317684 @default.
• W2013243372 hasConcept C126322002 @default.
• W2013243372 hasConcept C134018914 @default.
• W2013243372 hasConcept C159047783 @default.
• W2013243372 hasConcept C173803235 @default.
• W2013243372 hasConcept C185592680 @default.
• W2013243372 hasConcept C2776735649 @default.
• W2013243372 hasConcept C2776797465 @default.
• W2013243372 hasConcept C2776925932 @default.
• W2013243372 hasConcept C2778827303 @default.
• W2013243372 hasConcept C2779134260 @default.
• W2013243372 hasConcept C2779610285 @default.
• W2013243372 hasConcept C2781131914 @default.
• W2013243372 hasConcept C3019804061 @default.
• W2013243372 hasConcept C51551487 @default.
• W2013243372 hasConcept C519581460 @default.
• W2013243372 hasConcept C53345823 @default.
• W2013243372 hasConcept C55493867 @default.
• W2013243372 hasConcept C57074206 @default.
• W2013243372 hasConcept C62478195 @default.
• W2013243372 hasConcept C71924100 @default.
• W2013243372 hasConcept C86803240 @default.
• W2013243372 hasConcept C95444343 @default.
• W2013243372 hasConceptScore W2013243372C104317684 @default.
• W2013243372 hasConceptScore W2013243372C126322002 @default.
• W2013243372 hasConceptScore W2013243372C134018914 @default.
• W2013243372 hasConceptScore W2013243372C159047783 @default.
• W2013243372 hasConceptScore W2013243372C173803235 @default.
• W2013243372 hasConceptScore W2013243372C185592680 @default.
• W2013243372 hasConceptScore W2013243372C2776735649 @default.
• W2013243372 hasConceptScore W2013243372C2776797465 @default.
• W2013243372 hasConceptScore W2013243372C2776925932 @default.
• W2013243372 hasConceptScore W2013243372C2778827303 @default.
• W2013243372 hasConceptScore W2013243372C2779134260 @default.

• next