FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2013246980> ?p ?o ?g. }

• W2013246980 endingPage "167" @default.
• W2013246980 startingPage "159" @default.
• W2013246980 abstract "In order to clarify the pathogenesis of porcine serum (PS)-induced rat liver fibrosis, three experiments differing in dose of PS or duration of treatment were performed on male Fischer 344 rats. The rats were given an intraperitoneal injection of PS twice a week for 3 to 16 weeks and euthanized 7 days after the last injection for each treatment group. Liver tissues from these animals were subjected to detailed morphological and immunohistochemical examinations. Biochemical tests on treated rat serum revealed an increase in globulin concentration but no elevation in AST, ALT and ALP activities. There were no relationships among the dose of PS, the extent of fibrosis, and the anti-PS antibody titer. A number of α-smooth muscle actin-positive non-myofibroblastic cells, desmin-positive cells, and lipofuscin-laden Kupffer cells were found around the central veins and in the fibrous septa. In advanced stages of fibrosis, a proliferation of elastic fibers were observed in the septa. These findings were considered to indicate gradually occurred hepatocellular necrosis. The vascular endothelial cells in the fibrous septa expressed factor VIII-related antigen, exhibited fenestration accompanied by basement membrane formation, and were surrounded by Ito cells. Most of the portal vein branches showed hypertrophic thickening of the smooth muscle layer, resulting in narrowing of the lumen. These vascular changes suggested that hemodynamic alterations of the intrahepatic circulation induced hepatocellular necrosis/apoptosis and played an important role in the pathogenesis of porcine serum-induced liver fibrosis in rats." @default.
• W2013246980 created "2016-06-24" @default.
• W2013246980 creator A5013880095 @default.
• W2013246980 creator A5020482614 @default.
• W2013246980 creator A5035025328 @default.
• W2013246980 creator A5076592756 @default.
• W2013246980 date "1997-01-01" @default.
• W2013246980 modified "2023-10-06" @default.
• W2013246980 title "Morphological and Immunohistochemical Studies on Porcine Serum-Induced Rat Liver Fibrosis" @default.
• W2013246980 cites W10467864 @default.
• W2013246980 cites W1441046873 @default.
• W2013246980 cites W1966915736 @default.
• W2013246980 cites W1967848051 @default.
• W2013246980 cites W1982038210 @default.
• W2013246980 cites W1983062597 @default.
• W2013246980 cites W2012050910 @default.
• W2013246980 cites W2012589817 @default.
• W2013246980 cites W2013736587 @default.
• W2013246980 cites W2018971514 @default.
• W2013246980 cites W2026167796 @default.
• W2013246980 cites W2030503702 @default.
• W2013246980 cites W2031807877 @default.
• W2013246980 cites W2040617968 @default.
• W2013246980 cites W2044930714 @default.
• W2013246980 cites W2055591310 @default.
• W2013246980 cites W2066279813 @default.
• W2013246980 cites W2076565789 @default.
• W2013246980 cites W2082829740 @default.
• W2013246980 cites W2083207241 @default.
• W2013246980 cites W2089843401 @default.
• W2013246980 cites W2094731629 @default.
• W2013246980 cites W2118858353 @default.
• W2013246980 cites W2130157555 @default.
• W2013246980 cites W2138385637 @default.
• W2013246980 cites W2143847406 @default.
• W2013246980 cites W2152580118 @default.
• W2013246980 cites W2164282498 @default.
• W2013246980 cites W2164724294 @default.
• W2013246980 cites W2214144666 @default.
• W2013246980 cites W2322811895 @default.
• W2013246980 cites W2344353429 @default.
• W2013246980 cites W2408980962 @default.
• W2013246980 cites W3140044300 @default.
• W2013246980 cites W344993305 @default.
• W2013246980 cites W776815294 @default.
• W2013246980 doi "https://doi.org/10.1292/jvms.59.159" @default.
• W2013246980 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9101474" @default.
• W2013246980 hasPublicationYear "1997" @default.
• W2013246980 type Work @default.
• W2013246980 sameAs 2013246980 @default.
• W2013246980 citedByCount "13" @default.
• W2013246980 countsByYear W20132469802014 @default.
• W2013246980 countsByYear W20132469802019 @default.
• W2013246980 crossrefType "journal-article" @default.
• W2013246980 hasAuthorship W2013246980A5013880095 @default.
• W2013246980 hasAuthorship W2013246980A5020482614 @default.
• W2013246980 hasAuthorship W2013246980A5035025328 @default.
• W2013246980 hasAuthorship W2013246980A5076592756 @default.
• W2013246980 hasBestOaLocation W20132469801 @default.
• W2013246980 hasConcept C126322002 @default.
• W2013246980 hasConcept C131631996 @default.
• W2013246980 hasConcept C134018914 @default.
• W2013246980 hasConcept C142724271 @default.
• W2013246980 hasConcept C185592680 @default.
• W2013246980 hasConcept C204232928 @default.
• W2013246980 hasConcept C2776193487 @default.
• W2013246980 hasConcept C2780159080 @default.
• W2013246980 hasConcept C2780496750 @default.
• W2013246980 hasConcept C2780559512 @default.
• W2013246980 hasConcept C2780942790 @default.
• W2013246980 hasConcept C503630168 @default.
• W2013246980 hasConcept C71924100 @default.
• W2013246980 hasConcept C86803240 @default.
• W2013246980 hasConceptScore W2013246980C126322002 @default.
• W2013246980 hasConceptScore W2013246980C131631996 @default.
• W2013246980 hasConceptScore W2013246980C134018914 @default.
• W2013246980 hasConceptScore W2013246980C142724271 @default.
• W2013246980 hasConceptScore W2013246980C185592680 @default.
• W2013246980 hasConceptScore W2013246980C204232928 @default.
• W2013246980 hasConceptScore W2013246980C2776193487 @default.
• W2013246980 hasConceptScore W2013246980C2780159080 @default.
• W2013246980 hasConceptScore W2013246980C2780496750 @default.
• W2013246980 hasConceptScore W2013246980C2780559512 @default.
• W2013246980 hasConceptScore W2013246980C2780942790 @default.
• W2013246980 hasConceptScore W2013246980C503630168 @default.
• W2013246980 hasConceptScore W2013246980C71924100 @default.
• W2013246980 hasConceptScore W2013246980C86803240 @default.
• W2013246980 hasIssue "3" @default.
• W2013246980 hasLocation W20132469801 @default.
• W2013246980 hasLocation W20132469802 @default.
• W2013246980 hasOpenAccess W2013246980 @default.
• W2013246980 hasPrimaryLocation W20132469801 @default.
• W2013246980 hasRelatedWork W142403880 @default.
• W2013246980 hasRelatedWork W1542686017 @default.
• W2013246980 hasRelatedWork W1991181552 @default.
• W2013246980 hasRelatedWork W2000714230 @default.
• W2013246980 hasRelatedWork W2043179988 @default.
• W2013246980 hasRelatedWork W2059605029 @default.

• next