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- W2013290508 abstract "Significance Through the use of massively parallel sequencing, we have demonstrated a spectrum of plasma DNA abnormalities in patients with systemic lupus erythematosus. These abnormalities include aberrant measured genomic representations, hypomethylation, and DNA fragment size shortening. The binding of anti-double–stranded DNA antibody to plasma DNA appears to be an important factor associated with these abnormalities. These findings provide valuable insights into the biology of plasma DNA in an autoimmune disease and have potential implications for the development of new molecular markers for systemic lupus erythematosus." @default.
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- W2013290508 date "2014-11-26" @default.
- W2013290508 modified "2023-10-14" @default.
- W2013290508 title "Plasma DNA aberrations in systemic lupus erythematosus revealed by genomic and methylomic sequencing" @default.
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- W2013290508 doi "https://doi.org/10.1073/pnas.1421126111" @default.
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