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- W2013295296 abstract "We report the preparation of 2′-α-F, 2′-β-F and 2′,2′-difluoro analogues of the leading anti-varicella zoster virus (VZV) pentylphenyl BCNA Cf 1743. VZV thymidine kinase showed the highest phosphorylating capacity for the β-fluoro derivative, that retained equal antiviral potency as the parent compound. In contrast, the α-fluoro- and 2′,2′-difluoro BCNA derivatives were markedly less (∼100-fold) antivirally active." @default.
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- W2013295296 date "2009-11-01" @default.
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- W2013295296 title "2′-Fluorosugar analogues of the highly potent anti-varicella-zoster virus bicyclic nucleoside analogue (BCNA) Cf 1743" @default.
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- W2013295296 doi "https://doi.org/10.1016/j.bmcl.2009.09.116" @default.
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