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• W2013307568 abstract "Abstract 1. 1. Glucose-1,6-diphosphate (Glc-l,6-P 2 ), the powerful regulator of glucose metabolism, was found to be strikingly decreased in muscle of old rats. 2. 2. This decrease may result from the increase in the activity of Glc-1,6-P 2 phosphatase, the enzyme which degradates Glc-1,6-P 2 . 3. 3. The fall in Glc-1,6-P 2 in old age was accompanied by a concomitant reduction in phosphoglucomutase activity. However, phosphofructokinase activity was elevated, most probably as a result of the decrease in ATP and increase in ADP and AMP. 4. 4. These results indicate that in the course of aging glycolytic capacity of muscle is not reduced and the alterations reflect a more anaerobic metabolism. 5. 5. We also found a marked rise in plasma creatine phosphokinase in old animals, which may point to membrane abnormalities." @default.
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• W2013307568 date "1981-01-01" @default.
• W2013307568 modified "2023-09-23" @default.
• W2013307568 title "Glucose-1,6-diphosphate and carbohydrate metabolism in skeletal muscle of old rats" @default.
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• W2013307568 doi "https://doi.org/10.1016/0020-711x(81)90084-7" @default.
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