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• W2013313286 abstract "1 A local pre-injection of 1 μg dexamethasone sodium phosphate strongly inhibited (> 60% inhibition at 3 h; P < 0.001 at all time points) the development of carrageenin-induced paw oedema in the rat induced by a subplantar injection of 0.1 ml, 2% carrageenin. 2 Coinjection of a polyclonal rabbit antiserum raised against human 1–188 recombinant lipocortin 1, which also recognised the rat protein, reversed the inhibitory action of dexamethasone (P < 0.05 at 4 h and 5 h). At the highest volume used (40 μl) control antisera were without any effect. 3 These data further support the concept that lipocortin 1 is involved in the anti-inflammatory mechanism of action of the glucocorticoids." @default.
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• W2013313286 date "1993-01-01" @default.
• W2013313286 modified "2023-09-27" @default.
• W2013313286 title "The local anti-inflammatory action of dexamethasone in the rat carrageenin oedema model is reversed by an antiserum to lipocortin 1" @default.
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• W2013313286 doi "https://doi.org/10.1111/j.1476-5381.1993.tb13440.x" @default.
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