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• W2013333624 abstract "BackgroundEndovascular aneurysm repair (EVAR) is associated with an improved perioperative mortality compared to open surgical repair. This benefit may reflect reduced incidence of microvascular and macrovascular thrombotic complications after EVAR.PurposeThe purpose of this study was to review and compare the effects of abdominal aortic aneurysm (AAA), open surgical repair, and EVAR on coagulation, fibrinolysis, and platelet activation.MethodsA MEDLINE (1966-2010) and Cochrane library search for articles relating to the effects of AAA, open surgical repair, and EVAR on hemostasis was performed utilizing and cross-linking terms such as clotting, fibrinolysis, AAA, EVAR, and open surgical repair. Studies with a small cohort of patients (less than 7) or in which values of assessed biomarkers were not included were rejected.ResultsAAA is associated with increased thrombin generation, activity, and fibrin turnover as evidenced by increased plasma levels of thrombin-antithrombin III-complex (TAT), activated protein C-protein C inhibitor (APC-PCI), fibrin-monomer-fibrinogen (FM-F), F1+2, fibrinogen, and D-dimer. The extent of hemostatic derangement correlates with the volume of intraluminal thrombus. This procoagulant state is exaggerated in the immediate perioperative period after both open surgical repair and EVAR, but is attenuated at medium-term follow-up although not normalized.ConclusionThe resultant prothrombotic diathesis after open surgical repair and EVAR may account for the high level of perioperative thrombotic complications. Endovascular aneurysm repair (EVAR) is associated with an improved perioperative mortality compared to open surgical repair. This benefit may reflect reduced incidence of microvascular and macrovascular thrombotic complications after EVAR. The purpose of this study was to review and compare the effects of abdominal aortic aneurysm (AAA), open surgical repair, and EVAR on coagulation, fibrinolysis, and platelet activation. A MEDLINE (1966-2010) and Cochrane library search for articles relating to the effects of AAA, open surgical repair, and EVAR on hemostasis was performed utilizing and cross-linking terms such as clotting, fibrinolysis, AAA, EVAR, and open surgical repair. Studies with a small cohort of patients (less than 7) or in which values of assessed biomarkers were not included were rejected. AAA is associated with increased thrombin generation, activity, and fibrin turnover as evidenced by increased plasma levels of thrombin-antithrombin III-complex (TAT), activated protein C-protein C inhibitor (APC-PCI), fibrin-monomer-fibrinogen (FM-F), F1+2, fibrinogen, and D-dimer. The extent of hemostatic derangement correlates with the volume of intraluminal thrombus. This procoagulant state is exaggerated in the immediate perioperative period after both open surgical repair and EVAR, but is attenuated at medium-term follow-up although not normalized. The resultant prothrombotic diathesis after open surgical repair and EVAR may account for the high level of perioperative thrombotic complications." @default.
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• W2013333624 date "2011-09-01" @default.
• W2013333624 modified "2023-10-11" @default.
• W2013333624 title "Coagulation, fibrinolysis, and platelet activation in patients undergoing open and endovascular repair of abdominal aortic aneurysm" @default.
• W2013333624 cites W1825221379 @default.
• W2013333624 cites W1826696488 @default.
• W2013333624 cites W1836880685 @default.
• W2013333624 cites W1838534864 @default.
• W2013333624 cites W1924175076 @default.
• W2013333624 cites W1964027048 @default.
• W2013333624 cites W1965103886 @default.
• W2013333624 cites W1965881611 @default.
• W2013333624 cites W1968368894 @default.
• W2013333624 cites W1968531169 @default.
• W2013333624 cites W1969887141 @default.
• W2013333624 cites W1970971840 @default.
• W2013333624 cites W1971257600 @default.
• W2013333624 cites W1972399546 @default.
• W2013333624 cites W1973854172 @default.
• W2013333624 cites W1975982713 @default.
• W2013333624 cites W1979116160 @default.
• W2013333624 cites W1990797815 @default.
• W2013333624 cites W1990921015 @default.
• W2013333624 cites W1997704585 @default.
• W2013333624 cites W1999243800 @default.
• W2013333624 cites W1999615698 @default.
• W2013333624 cites W2004545364 @default.
• W2013333624 cites W2006218093 @default.
• W2013333624 cites W2007907287 @default.
• W2013333624 cites W2009383527 @default.
• W2013333624 cites W2010004644 @default.
• W2013333624 cites W2013212009 @default.
• W2013333624 cites W2014690503 @default.
• W2013333624 cites W2017559656 @default.
• W2013333624 cites W2021145842 @default.
• W2013333624 cites W2022342764 @default.
• W2013333624 cites W2024641271 @default.
• W2013333624 cites W2032048318 @default.
• W2013333624 cites W2036097309 @default.
• W2013333624 cites W2037724346 @default.
• W2013333624 cites W2038780185 @default.
• W2013333624 cites W2039343177 @default.
• W2013333624 cites W2043896912 @default.
• W2013333624 cites W2043915579 @default.
• W2013333624 cites W2051536097 @default.
• W2013333624 cites W2052219120 @default.
• W2013333624 cites W2053418973 @default.
• W2013333624 cites W2056748674 @default.
• W2013333624 cites W2057323160 @default.
• W2013333624 cites W2061869498 @default.
• W2013333624 cites W2063817896 @default.
• W2013333624 cites W2066676897 @default.
• W2013333624 cites W2070248706 @default.
• W2013333624 cites W2070455340 @default.
• W2013333624 cites W2070970206 @default.
• W2013333624 cites W2071286923 @default.
• W2013333624 cites W2077523233 @default.
• W2013333624 cites W2078673233 @default.
• W2013333624 cites W2079053385 @default.
• W2013333624 cites W2081060841 @default.
• W2013333624 cites W2084124265 @default.
• W2013333624 cites W2084899396 @default.
• W2013333624 cites W2085881657 @default.
• W2013333624 cites W2085993135 @default.
• W2013333624 cites W2090662934 @default.
• W2013333624 cites W2093198834 @default.
• W2013333624 cites W2093365874 @default.
• W2013333624 cites W2094008101 @default.
• W2013333624 cites W2094743529 @default.
• W2013333624 cites W2098076038 @default.
• W2013333624 cites W2110882504 @default.
• W2013333624 cites W2113037319 @default.
• W2013333624 cites W2115347479 @default.
• W2013333624 cites W2115902832 @default.
• W2013333624 cites W2118757180 @default.
• W2013333624 cites W2126885182 @default.
• W2013333624 cites W2142292251 @default.
• W2013333624 cites W2146051938 @default.
• W2013333624 cites W2146734864 @default.
• W2013333624 cites W2158955649 @default.
• W2013333624 cites W2410137123 @default.
• W2013333624 cites W2414391836 @default.
• W2013333624 cites W2417436195 @default.
• W2013333624 cites W4235125751 @default.
• W2013333624 cites W4294570513 @default.
• W2013333624 cites W83185956 @default.
• W2013333624 doi "https://doi.org/10.1016/j.jvs.2011.04.010" @default.
• W2013333624 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21684711" @default.
• W2013333624 hasPublicationYear "2011" @default.
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