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• W2013359571 abstract "No AccessJournal of UrologyAdult Urology1 Jun 2008Oncological Evaluation of Prostate Sparing Cystectomy: The Montsouris Long-Term Results François Rozet, Guillaume Lesur, Xavier Cathelineau, Eric Barret, Gordon Smyth, Shawn Soon, and Guy Vallancien François RozetFrançois Rozet More articles by this author , Guillaume LesurGuillaume Lesur More articles by this author , Xavier CathelineauXavier Cathelineau More articles by this author , Eric BarretEric Barret More articles by this author , Gordon SmythGordon Smyth More articles by this author , Shawn SoonShawn Soon More articles by this author , and Guy VallancienGuy Vallancien More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2008.01.112AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: Prostate sparing cystectomy provides an alternative therapeutic option in highly selected patients with invasive bladder cancer who wish to avoid the significant functional side effects of traditional surgery. Concern exists regarding the oncological safety of this technique especially with regard to the presence of prostatic urothelial cancer and incidental prostate adenocarcinoma. We present the long-term oncological outcomes of a large series of patients treated at a single institution. Materials and Methods: Between October 1992 and June 2004 a total of 117 patients were selected for prostate sparing cystectomy after meeting the inclusion criteria. Results: Nine patients underwent radical cystoprostatectomy after prostate urothelial carcinoma was diagnosed intraoperatively. Long-term oncological results (2 years minimum followup [mean 55 months]) are presented here for the remaining patients. The rate of local and distant recurrence was 4.7% and 34%, respectively, at 20 months. Overall survival at 5 years in our study was 67%, and 5-year disease-free survival rates were 77% for pT2 N0 or less, 44% for pT3 N0 or greater and 22% for pN+ disease. Of 6 patients found to have prostate adenocarcinoma in transurethral prostate resection specimens 1 was treated with high intensity focused ultrasound and 5 were followed with active surveillance, 2 of whom later died of bladder cancer. Conclusions: We report oncological data on the largest prospective cohort of patients, with the longest followup, treated by prostate sparing cystectomy to date. Outcomes are comparable with the largest published series of cystoprosatectomies. With appropriate screening the risk of a clinically significant prostate cancer appears to be low. For certain selected patients this technique represents a valuable additional option for treatment. References 1 : Reconstruction of the urinary tract after radical cystectomy: the case for continent urinary diversion. Urology1997; 49: 663. Google Scholar 2 : Impotence following radical prostatectomy: insight into etiology and prevention. J Urol1982; 128: 492. 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Link, Google Scholar Department of Urology, Institut Mutualiste Montsouris and Université Paris Descartes, Paris, France© 2008 by American Urological AssociationFiguresReferencesRelatedDetailsCited byFurrer M, Kiss B, Studer U, Wuethrich P, Gahl B, Seiler R, Roth B, Bosshard P, Thomas B, Burkhard F, Boxler S and Thalmann G (2021) Seminal Vesical Sparing Cystectomy for Bladder Cancer is Feasible with Good Functional Results without Impairing Oncological Outcomes: A Longitudinal Long-Term Propensity-Matched Single Center StudyJournal of Urology, VOL. 205, NO. 6, (1629-1640), Online publication date: 1-Jun-2021.Mertens L, Meijer R, de Vries R, Nieuwenhuijzen J, van der Poel H, Bex A, van Rhijn B, Meinhardt W and Horenblas S (2013) Prostate Sparing Cystectomy for Bladder Cancer: 20-Year Single Center ExperienceJournal of Urology, VOL. 191, NO. 5, (1250-1255), Online publication date: 1-May-2014.Bruins H, Djaladat H, Ahmadi H, Sherrod A, Cai J, Miranda G, Skinner E and Daneshmand S (2013) Incidental Prostate Cancer in Patients with Bladder Urothelial Carcinoma: Comprehensive Analysis of 1,476 Radical Cystoprostatectomy SpecimensJournal of Urology, VOL. 190, NO. 5, (1704-1709), Online publication date: 1-Nov-2013. Volume 179Issue 6June 2008Page: 2170-2175 Advertisement Copyright & Permissions© 2008 by American Urological AssociationKeywordsurinary bladder neoplasmscystectomyprostatectomytreatment outcomeprostatic neoplasmsMetricsAuthor Information François Rozet More articles by this author Guillaume Lesur More articles by this author Xavier Cathelineau More articles by this author Eric Barret More articles by this author Gordon Smyth More articles by this author Shawn Soon More articles by this author Guy Vallancien More articles by this author Expand All Advertisement PDF downloadLoading ..." @default.
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