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• W2013381736 abstract "Long-term potentiation (LTP) in the hippocampus is a long lasting enhancement of the postsynaptic evoked response following high frequency, repetitive stimulation of afferents. The extracellularly recorded action potential (population spike) can be reversibly blocked, without affecting the extracellular recorded excitatory postsynaptic potential, by focal application of γ-aminobutyric acid, tetrodotoxin, or pentobarbital, to the CA1 pyramidal cells of the hippocampal slice. When the population spike is blocked during repetitive stimulation, LTP does not occur. It appears that postsynaptic firing of action potentials during repetitive stimulation is necessary to produce LTP." @default.
• W2013381736 created "2016-06-24" @default.
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• W2013381736 date "1985-04-01" @default.
• W2013381736 modified "2023-10-10" @default.
• W2013381736 title "Postsynaptic firing during repetitive stimulation is required for long-term potentiation in hippocampus" @default.
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• W2013381736 doi "https://doi.org/10.1016/0006-8993(85)91552-5" @default.
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