Matches in SemOpenAlex for { <https://semopenalex.org/work/W2013399275> ?p ?o ?g. }
- W2013399275 endingPage "670" @default.
- W2013399275 startingPage "655" @default.
- W2013399275 abstract "The concept of the immutability of the nervous tissue has recently been replaced with the new idea that a continuous neurogenic turnover does occur in some limited areas of the central nervous system (CNS). At least two neurogenic regions of the adult mammalian CNS are involved in this process: the subventricular zone of the forebrain and the dentate gyrus of the hippocampus, which are considered to be a reservoir of new neural cells. Neural stem cells (NSCs) are multipotential progenitors that have self-renewal capability. While in vivo endogenous NSCs seem able to produce almost exclusively neurons, a single NSC in vitro is competent to generate neurons, astrocytes, and oligodendrocytes. NSCs lack a specific morphology and unambiguous surface markers that could allow their identification. For this reason, one of the major difficulties in identifying stem cells is that they are defined in terms of their functional capabilities, the determination of which might alter the cells' nature. The purpose of this review is to describe the characteristics of the NSCs of the adult mammalian CNS, their potentiality in terms of proliferation and differentiation capabilities, as well as their stability in long-term culture, all attributes that make them a good tool for tissue replacement therapies." @default.
- W2013399275 created "2016-06-24" @default.
- W2013399275 creator A5020814680 @default.
- W2013399275 creator A5026666624 @default.
- W2013399275 creator A5028268191 @default.
- W2013399275 creator A5064655713 @default.
- W2013399275 creator A5069765619 @default.
- W2013399275 creator A5076344718 @default.
- W2013399275 creator A5079554474 @default.
- W2013399275 date "2003-12-01" @default.
- W2013399275 modified "2023-10-03" @default.
- W2013399275 title "Neural Stem Cells in the Adult Nervous System" @default.
- W2013399275 cites W1001099587 @default.
- W2013399275 cites W116758555 @default.
- W2013399275 cites W122639779 @default.
- W2013399275 cites W1482293895 @default.
- W2013399275 cites W1483365010 @default.
- W2013399275 cites W1487852103 @default.
- W2013399275 cites W1487914405 @default.
- W2013399275 cites W1513170871 @default.
- W2013399275 cites W1527244616 @default.
- W2013399275 cites W1570521101 @default.
- W2013399275 cites W1592283056 @default.
- W2013399275 cites W1621991227 @default.
- W2013399275 cites W1643680178 @default.
- W2013399275 cites W1817027815 @default.
- W2013399275 cites W1838548664 @default.
- W2013399275 cites W1840746752 @default.
- W2013399275 cites W1859089489 @default.
- W2013399275 cites W1859730138 @default.
- W2013399275 cites W1899815911 @default.
- W2013399275 cites W1918331015 @default.
- W2013399275 cites W1922961861 @default.
- W2013399275 cites W1938346635 @default.
- W2013399275 cites W1963980352 @default.
- W2013399275 cites W1964451213 @default.
- W2013399275 cites W1964607223 @default.
- W2013399275 cites W1965425054 @default.
- W2013399275 cites W1967958787 @default.
- W2013399275 cites W1970416276 @default.
- W2013399275 cites W1971908211 @default.
- W2013399275 cites W1975203903 @default.
- W2013399275 cites W1976795542 @default.
- W2013399275 cites W1977215237 @default.
- W2013399275 cites W1979480778 @default.
- W2013399275 cites W1980499453 @default.
- W2013399275 cites W1981250983 @default.
- W2013399275 cites W1983725263 @default.
- W2013399275 cites W1983955843 @default.
- W2013399275 cites W1985244709 @default.
- W2013399275 cites W1987107175 @default.
- W2013399275 cites W1987144806 @default.
- W2013399275 cites W1987145582 @default.
- W2013399275 cites W1988671949 @default.
- W2013399275 cites W1989692142 @default.
- W2013399275 cites W1994042895 @default.
- W2013399275 cites W1996822067 @default.
- W2013399275 cites W1997447798 @default.
- W2013399275 cites W1998502499 @default.
- W2013399275 cites W2002070218 @default.
- W2013399275 cites W2003861928 @default.
- W2013399275 cites W2005017965 @default.
- W2013399275 cites W2007242343 @default.
- W2013399275 cites W2012928251 @default.
- W2013399275 cites W2013485257 @default.
- W2013399275 cites W2018657730 @default.
- W2013399275 cites W2023792909 @default.
- W2013399275 cites W2025772448 @default.
- W2013399275 cites W2030508161 @default.
- W2013399275 cites W2031874070 @default.
- W2013399275 cites W2035250926 @default.
- W2013399275 cites W2037872087 @default.
- W2013399275 cites W2046006021 @default.
- W2013399275 cites W2051575011 @default.
- W2013399275 cites W2051615377 @default.
- W2013399275 cites W2053883738 @default.
- W2013399275 cites W2054264241 @default.
- W2013399275 cites W2055561480 @default.
- W2013399275 cites W2058311433 @default.
- W2013399275 cites W2059817147 @default.
- W2013399275 cites W2060572966 @default.
- W2013399275 cites W2064960897 @default.
- W2013399275 cites W2065737043 @default.
- W2013399275 cites W2065762908 @default.
- W2013399275 cites W2067161293 @default.
- W2013399275 cites W2067198472 @default.
- W2013399275 cites W2072881342 @default.
- W2013399275 cites W2075626955 @default.
- W2013399275 cites W2077220534 @default.
- W2013399275 cites W2077439063 @default.
- W2013399275 cites W2078504009 @default.
- W2013399275 cites W2079244950 @default.
- W2013399275 cites W2079341754 @default.
- W2013399275 cites W2079356804 @default.
- W2013399275 cites W2082026841 @default.
- W2013399275 cites W2083075869 @default.
- W2013399275 cites W2083357861 @default.
- W2013399275 cites W2083579647 @default.