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• W2013402672 abstract "The initiation of a cultured human colon carcinoma line on a feeder layer of confluent fibroblasts is described. Attempts to initiate cultures without fibroblast feeder layers were not successful. Two sub-lines (designated HCT C and HCT C Col) were isolated and weaned from cells growing on the surface of the feeder layer. The sub-lines had different morphologies, secreted different levels of carcinoembryonic antigen (CEA) into the medium of confluent cultures and had slightly different karyotypes. Both sub-lines grew in semi-solid medium and formed xenografts when injected s.c. into athymic nude mice. Analysis of radioiodinated cell membrane components indicated small, but significant differences between the sub-lines." @default.
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• W2013402672 date "1983-03-01" @default.
• W2013402672 modified "2023-10-06" @default.
• W2013402672 title "Characterization of human colon carcinoma cell lines isolated from a single primary tumour" @default.
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• W2013402672 doi "https://doi.org/10.1038/bjc.1983.56" @default.
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