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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2013407711> ?p ?o ?g. }

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• W2013407711 abstract "It is postulated that Parkinson's disease is the result of environmental factors acting on genetically susceptible individuals against a background of normal ageing. Many potentially neurotoxic xenobiotics are detoxified by hepatic cytochrome P450. The function of one such system was studied in forty patients with Parkinson's disease and forty normal control subjects. Significantly more parkinsonian than control subjects had partially or totally defective 4-hydroxylation of debrisoquine. Poor metabolisers of debrisoquine tended to have had earlier onset of disease." @default.
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• W2013407711 date "1985-11-01" @default.
• W2013407711 modified "2023-10-09" @default.
• W2013407711 title "ECOGENETICS OF PARKINSON'S DISEASE: 4-HYDROXYLATION OF DEBRISOQUINE" @default.
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• W2013407711 doi "https://doi.org/10.1016/s0140-6736(85)90743-3" @default.
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