FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2013437260> ?p ?o ?g. }

• W2013437260 endingPage "575" @default.
• W2013437260 startingPage "569" @default.
• W2013437260 abstract "Present-day oncology sees at least two-thirds of cancer patients receiving radiation therapy as a part of their anticancer treatment. The objectives of the current study were to investigate the effects of the small molecule inhibitors of Wee1 kinase II (681641) and Rad51 (RI-1) on cell cycle progression, DNA double-strand breaks repair and apoptosis following ionizing radiation exposure in human leukemic T-cells Jurkat and MOLT-4. Pre-treatment with the Wee1 681641 or Rad51 RI-1 inhibitor alone increased the sensitivity of Jurkat cells to irradiation, however combining both inhibitors together resulted in a further enhancement of apoptosis. Jurkat cells pre-treated with inhibitors were positive for γH2AX foci 24h upon irradiation. MOLT-4 cells were less affected by inhibitors application prior to ionizing radiation exposure. Pre-treatment with Rad51 RI-1 had no effect on apoptosis induction; however Wee1 681641 increased ionizing radiation-induced cell death in MOLT-4 cells." @default.
• W2013437260 created "2016-06-24" @default.
• W2013437260 creator A5003499858 @default.
• W2013437260 creator A5013420163 @default.
• W2013437260 creator A5022514220 @default.
• W2013437260 creator A5040363021 @default.
• W2013437260 creator A5062290336 @default.
• W2013437260 creator A5071373861 @default.
• W2013437260 creator A5075281894 @default.
• W2013437260 creator A5078226465 @default.
• W2013437260 creator A5087493118 @default.
• W2013437260 date "2014-10-01" @default.
• W2013437260 modified "2023-09-30" @default.
• W2013437260 title "Specific inhibition of Wee1 kinase and Rad51 recombinase: A strategy to enhance the sensitivity of leukemic T-cells to ionizing radiation-induced DNA double-strand breaks" @default.
• W2013437260 cites W1515564094 @default.
• W2013437260 cites W2002501210 @default.
• W2013437260 cites W2002573912 @default.
• W2013437260 cites W2069965829 @default.
• W2013437260 cites W2089574530 @default.
• W2013437260 cites W2099607826 @default.
• W2013437260 cites W2113283898 @default.
• W2013437260 cites W2125972940 @default.
• W2013437260 cites W2126404651 @default.
• W2013437260 cites W2133150002 @default.
• W2013437260 cites W2138741985 @default.
• W2013437260 cites W2142325694 @default.
• W2013437260 cites W63001887 @default.
• W2013437260 doi "https://doi.org/10.1016/j.bbrc.2014.09.123" @default.
• W2013437260 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25285634" @default.
• W2013437260 hasPublicationYear "2014" @default.
• W2013437260 type Work @default.
• W2013437260 sameAs 2013437260 @default.
• W2013437260 citedByCount "13" @default.
• W2013437260 countsByYear W20134372602015 @default.
• W2013437260 countsByYear W20134372602016 @default.
• W2013437260 countsByYear W20134372602018 @default.
• W2013437260 countsByYear W20134372602019 @default.
• W2013437260 countsByYear W20134372602020 @default.
• W2013437260 countsByYear W20134372602022 @default.
• W2013437260 countsByYear W20134372602023 @default.
• W2013437260 crossrefType "journal-article" @default.
• W2013437260 hasAuthorship W2013437260A5003499858 @default.
• W2013437260 hasAuthorship W2013437260A5013420163 @default.
• W2013437260 hasAuthorship W2013437260A5022514220 @default.
• W2013437260 hasAuthorship W2013437260A5040363021 @default.
• W2013437260 hasAuthorship W2013437260A5062290336 @default.
• W2013437260 hasAuthorship W2013437260A5071373861 @default.
• W2013437260 hasAuthorship W2013437260A5075281894 @default.
• W2013437260 hasAuthorship W2013437260A5078226465 @default.
• W2013437260 hasAuthorship W2013437260A5087493118 @default.
• W2013437260 hasConcept C111337013 @default.
• W2013437260 hasConcept C120504264 @default.
• W2013437260 hasConcept C121332964 @default.
• W2013437260 hasConcept C121608353 @default.
• W2013437260 hasConcept C134935766 @default.
• W2013437260 hasConcept C143425029 @default.
• W2013437260 hasConcept C153911025 @default.
• W2013437260 hasConcept C179464577 @default.
• W2013437260 hasConcept C18231593 @default.
• W2013437260 hasConcept C184235292 @default.
• W2013437260 hasConcept C185544564 @default.
• W2013437260 hasConcept C190283241 @default.
• W2013437260 hasConcept C203014093 @default.
• W2013437260 hasConcept C26114605 @default.
• W2013437260 hasConcept C2776090121 @default.
• W2013437260 hasConcept C2779012473 @default.
• W2013437260 hasConcept C2781252693 @default.
• W2013437260 hasConcept C29537977 @default.
• W2013437260 hasConcept C502942594 @default.
• W2013437260 hasConcept C54355233 @default.
• W2013437260 hasConcept C552990157 @default.
• W2013437260 hasConcept C86803240 @default.
• W2013437260 hasConcept C8891405 @default.
• W2013437260 hasConcept C95444343 @default.
• W2013437260 hasConcept C96232424 @default.
• W2013437260 hasConceptScore W2013437260C111337013 @default.
• W2013437260 hasConceptScore W2013437260C120504264 @default.
• W2013437260 hasConceptScore W2013437260C121332964 @default.
• W2013437260 hasConceptScore W2013437260C121608353 @default.
• W2013437260 hasConceptScore W2013437260C134935766 @default.
• W2013437260 hasConceptScore W2013437260C143425029 @default.
• W2013437260 hasConceptScore W2013437260C153911025 @default.
• W2013437260 hasConceptScore W2013437260C179464577 @default.
• W2013437260 hasConceptScore W2013437260C18231593 @default.
• W2013437260 hasConceptScore W2013437260C184235292 @default.
• W2013437260 hasConceptScore W2013437260C185544564 @default.
• W2013437260 hasConceptScore W2013437260C190283241 @default.
• W2013437260 hasConceptScore W2013437260C203014093 @default.
• W2013437260 hasConceptScore W2013437260C26114605 @default.
• W2013437260 hasConceptScore W2013437260C2776090121 @default.
• W2013437260 hasConceptScore W2013437260C2779012473 @default.
• W2013437260 hasConceptScore W2013437260C2781252693 @default.
• W2013437260 hasConceptScore W2013437260C29537977 @default.
• W2013437260 hasConceptScore W2013437260C502942594 @default.
• W2013437260 hasConceptScore W2013437260C54355233 @default.
• W2013437260 hasConceptScore W2013437260C552990157 @default.
• W2013437260 hasConceptScore W2013437260C86803240 @default.
• W2013437260 hasConceptScore W2013437260C8891405 @default.

• next