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- W2013447013 abstract "The present paper aims to evaluate the physico-chemical and biocompatible properties of some new nanostructured hydroxyapatite-polyurethane (HAP-PU) composite scaffolds in direct contact with MSCs by in vitro tests. Several HAP based nanostructures were obtained by hydrothermal synthesis in various pressure conditions, i.e. pressure varying between 20-80 atm and temperature less than 1000 C. For the first time, a polyurethane with 100% hard segment content with carboxyl functional groups was used to prepare ceramic-polymer composites (80% HAP) with potential applications in bone tissue engineering. HAP crystallites with 15-35 nm in length were obtained. The results of MSCs viability indicated a slightly higher viability of HAP coatings (72% vs. control) compared to HAP-PU composites (69% vs. control) synthesized at high pressure (60 atm). This could be due to the effect of particle shape on cellular viability." @default.
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- W2013447013 date "2012-07-01" @default.
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- W2013447013 title "Physico-chemical and biocompatible properties of hydroxyapatite based composites prepared by an innovative synthesis route" @default.
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- W2013447013 doi "https://doi.org/10.1016/j.matlet.2012.03.099" @default.
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