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• W2013453334 startingPage "268" @default.
• W2013453334 abstract "Insulin resistance is frequently associated with chronic liver disease, and the interaction between hepatitis C virus (HCV) infection and insulin resistance is a major public health issue, bound to increase in the near term. Because of their potential synergism on liver disease severity, a better understanding of the clinical consequences of the relationship between HCV infection and insulin resistance is needed. This translates into accelerated liver disease progression, reduced response to anti-viral agents and, in susceptible individuals, increased risk of developing type 2 diabetes. HCV may also cause hepatic steatosis, especially in patients infected with genotype 3, although the clinical impact of viral steatosis is debated. Little is known regarding the effect of anti-diabetic agents on HCV infection, and a possible association between use of exogenous insulin or a sulfonylurea agents and the development of hepatocellular carcinoma has recently been reported. Thus, modified lifestyle and pharmacological modalities are urgently warranted in chronic hepatitis C with metabolic alterations." @default.
• W2013453334 created "2016-06-24" @default.
• W2013453334 creator A5025330168 @default.
• W2013453334 date "2012-01-01" @default.
• W2013453334 modified "2023-09-28" @default.
• W2013453334 title "Chronic Hepatitis C and Insulin Resistance" @default.
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• W2013453334 doi "https://doi.org/10.4166/kjg.2012.59.4.268" @default.
• W2013453334 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22544023" @default.
• W2013453334 hasPublicationYear "2012" @default.
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