FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2013463715> ?p ?o ?g. }

• W2013463715 endingPage "410" @default.
• W2013463715 startingPage "403" @default.
• W2013463715 abstract "Transforming growth factor-β (TGF-β) is the prototype of a family of secreted polypeptide growth factors. These cytokines play very important roles during development, as well as in normal physiological and disease processes, by regulating a wide array of cellular processes, such as cell growth, differentiation, migration, apoptosis, and extracellular matrix production. TGF-β utilizes a multitude of intracellular signalling pathways in addition to Smads with actions that are dependent on circumstances, including dose, target cell type, and context. The aims of this research were (i) to verify the effects of dose-dependent TGF-β3 treatment on YY1 and p53 expression, in BPH-1 cell line, human benign prostate hyperplasia, and two prostate cancer cell lines, LNCaP, which is androgen-sensitive, and DU-145, which is androgen-non responsive, (ii) establish a correlation between p53 and YY1 and (iii) determine the expression of a number of important intracellular signalling pathways in TGF-β3-treated prostate cell lines. The expression of YY1, p53, PI3K, AKT, pAKT, PTEN, Bcl-2, Bax, and iNOS was evaluated through Western blot analysis on BPH-1, LNCaP, and DU-145 cultures treated with 10 and 50 ng/ml of TGF-β3 for 24 h. The production of nitric oxide (NO) was determined by Griess reagent and cell viability through MTT assay. The results of this research demonstrated profound differences in the responses of the BPH-1, LNCaP, and DU-145 cell lines to TGF-β3 stimulation. We believe that the findings could be important because of the clinical relevance that they may assume and the therapeutic implications for TGF-β treatment of prostate cancer." @default.
• W2013463715 created "2016-06-24" @default.
• W2013463715 creator A5010708987 @default.
• W2013463715 creator A5015437100 @default.
• W2013463715 creator A5039656353 @default.
• W2013463715 creator A5090329746 @default.
• W2013463715 date "2011-11-01" @default.
• W2013463715 modified "2023-09-27" @default.
• W2013463715 title "Modulation of YY1 and p53 expression by transforming growth factor-β3 in prostate cell lines" @default.
• W2013463715 cites W1483898176 @default.
• W2013463715 cites W1556295515 @default.
• W2013463715 cites W1571688489 @default.
• W2013463715 cites W1930083400 @default.
• W2013463715 cites W1963966851 @default.
• W2013463715 cites W1965581435 @default.
• W2013463715 cites W1969619516 @default.
• W2013463715 cites W1981327848 @default.
• W2013463715 cites W1983628734 @default.
• W2013463715 cites W1984162437 @default.
• W2013463715 cites W1984418041 @default.
• W2013463715 cites W1991494214 @default.
• W2013463715 cites W1991736202 @default.
• W2013463715 cites W1992981111 @default.
• W2013463715 cites W1995514235 @default.
• W2013463715 cites W1999587518 @default.
• W2013463715 cites W2006313701 @default.
• W2013463715 cites W2017246544 @default.
• W2013463715 cites W2024969918 @default.
• W2013463715 cites W2032313226 @default.
• W2013463715 cites W2034112780 @default.
• W2013463715 cites W2042760441 @default.
• W2013463715 cites W2044561872 @default.
• W2013463715 cites W2049952383 @default.
• W2013463715 cites W2051373106 @default.
• W2013463715 cites W2055086507 @default.
• W2013463715 cites W2058135827 @default.
• W2013463715 cites W2060218681 @default.
• W2013463715 cites W2060972565 @default.
• W2013463715 cites W2062757512 @default.
• W2013463715 cites W2066549657 @default.
• W2013463715 cites W2067258802 @default.
• W2013463715 cites W2067751798 @default.
• W2013463715 cites W2069360248 @default.
• W2013463715 cites W2069524101 @default.
• W2013463715 cites W2071119950 @default.
• W2013463715 cites W2076676971 @default.
• W2013463715 cites W2078830718 @default.
• W2013463715 cites W2080777964 @default.
• W2013463715 cites W2081843959 @default.
• W2013463715 cites W2082979850 @default.
• W2013463715 cites W2098313619 @default.
• W2013463715 cites W2102298863 @default.
• W2013463715 cites W2103031848 @default.
• W2013463715 cites W2104744253 @default.
• W2013463715 cites W2109990295 @default.
• W2013463715 cites W2118456764 @default.
• W2013463715 cites W2125690417 @default.
• W2013463715 cites W2134102934 @default.
• W2013463715 cites W2147754310 @default.
• W2013463715 cites W2158301564 @default.
• W2013463715 cites W2163386603 @default.
• W2013463715 cites W2324808718 @default.
• W2013463715 cites W2388163742 @default.
• W2013463715 cites W4245164766 @default.
• W2013463715 doi "https://doi.org/10.1016/j.cyto.2011.06.024" @default.
• W2013463715 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21807531" @default.
• W2013463715 hasPublicationYear "2011" @default.
• W2013463715 type Work @default.
• W2013463715 sameAs 2013463715 @default.
• W2013463715 citedByCount "11" @default.
• W2013463715 countsByYear W20134637152012 @default.
• W2013463715 countsByYear W20134637152013 @default.
• W2013463715 countsByYear W20134637152014 @default.
• W2013463715 countsByYear W20134637152015 @default.
• W2013463715 countsByYear W20134637152017 @default.
• W2013463715 countsByYear W20134637152022 @default.
• W2013463715 crossrefType "journal-article" @default.
• W2013463715 hasAuthorship W2013463715A5010708987 @default.
• W2013463715 hasAuthorship W2013463715A5015437100 @default.
• W2013463715 hasAuthorship W2013463715A5039656353 @default.
• W2013463715 hasAuthorship W2013463715A5090329746 @default.
• W2013463715 hasConcept C118131993 @default.
• W2013463715 hasConcept C121608353 @default.
• W2013463715 hasConcept C170493617 @default.
• W2013463715 hasConcept C185592680 @default.
• W2013463715 hasConcept C2775960820 @default.
• W2013463715 hasConcept C2779723316 @default.
• W2013463715 hasConcept C2780192828 @default.
• W2013463715 hasConcept C502942594 @default.
• W2013463715 hasConcept C54355233 @default.
• W2013463715 hasConcept C55493867 @default.
• W2013463715 hasConcept C62112901 @default.
• W2013463715 hasConcept C81885089 @default.
• W2013463715 hasConcept C86803240 @default.
• W2013463715 hasConcept C95444343 @default.
• W2013463715 hasConceptScore W2013463715C118131993 @default.
• W2013463715 hasConceptScore W2013463715C121608353 @default.
• W2013463715 hasConceptScore W2013463715C170493617 @default.

• next