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- W2013467319 abstract "Abstract The effects of FK506, a potent immunosuppressive drug, on hepatocarcinogenesis were investigated using a medium-term liver bioassay model based on the induction of glutathione S-transferase placental form (GST-P)-positive preneoplastic foci and by studies on liver cell regeneration after two-thirds partial hepatectomy (PH). In Experiment 1, daily FK506 administration, 0.5 or 1.0 mg kg−1 by gastric intubation, increased the areas of GST-P-positive foci in male F344 rats (P" @default.
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- W2013467319 date "1998-01-01" @default.
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- W2013467319 title "Effects of tacrolimus (FK506) on induction of glutathione S-transferase P-positive foci and liver cell regeneration after partial hepatectomy in F344 rats" @default.
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- W2013467319 doi "https://doi.org/10.1016/s1386-6346(97)00101-0" @default.
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