FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2013502079> ?p ?o ?g. }

• W2013502079 endingPage "1003" @default.
• W2013502079 startingPage "998" @default.
• W2013502079 abstract "Background: Human anxiety disorders are complex diseases with relatively unknown etiology. Dysfunction of the Gamma-aminobutyric acid (GABA) system has been implicated in many neuropsychiatric conditions, including anxiety and depressive disorders. In this investigation, we explored four GABA receptor genes for their possible associations with genetic risk for anxiety disorders and depression.Methods: Our study sample consisted of 589 cases and 539 controls selected from a large population-based twin registry based upon a latent genetic risk factor shared by several anxiety disorders, major depression, and neuroticism. We subjected these to a two-stage protocol, in which all candidate genetic markers were screened for association in stage 1 (N=376), the positive results of which were tested for replication in stage 2 (N=752). We analyzed data from 26 single nucleotide polymorphisms (SNPs) from four GABA receptor genes: GABRA2, GABRA3, GABRA6, and GABRG2. Results: Of the 26 SNPs genotyped in stage 1, we identified two markers in GABRA3 that met the threshold (P≤.1) to be tested in stage 2. Phenotypic associations of these two markers failed to replicate in stage 2. Conclusions: These findings suggest that common variation in the GABRA2, GABRA3, GABRA6, and GABRG2 genes does not play a major role in liability to anxiety spectrum disorders. Depression and Anxiety 26:998–1003, 2009. Published 2009 Wiley-Liss, Inc." @default.
• W2013502079 created "2016-06-24" @default.
• W2013502079 creator A5008171523 @default.
• W2013502079 creator A5011961838 @default.
• W2013502079 creator A5019911642 @default.
• W2013502079 creator A5027640245 @default.
• W2013502079 creator A5044019481 @default.
• W2013502079 creator A5049231102 @default.
• W2013502079 creator A5050191788 @default.
• W2013502079 date "2009-11-01" @default.
• W2013502079 modified "2023-10-16" @default.
• W2013502079 title "Association study between GABA receptor genes and anxiety spectrum disorders" @default.
• W2013502079 cites W1602497443 @default.
• W2013502079 cites W1975516199 @default.
• W2013502079 cites W1977130990 @default.
• W2013502079 cites W1977887774 @default.
• W2013502079 cites W1981049931 @default.
• W2013502079 cites W1981879624 @default.
• W2013502079 cites W1983585786 @default.
• W2013502079 cites W1990779093 @default.
• W2013502079 cites W1991475702 @default.
• W2013502079 cites W2000068974 @default.
• W2013502079 cites W2022378061 @default.
• W2013502079 cites W2038693055 @default.
• W2013502079 cites W2040309911 @default.
• W2013502079 cites W2058401000 @default.
• W2013502079 cites W2060606855 @default.
• W2013502079 cites W2070640104 @default.
• W2013502079 cites W2072701815 @default.
• W2013502079 cites W2075492585 @default.
• W2013502079 cites W2090116461 @default.
• W2013502079 cites W2105394148 @default.
• W2013502079 cites W2110424682 @default.
• W2013502079 cites W2114634718 @default.
• W2013502079 cites W2118929411 @default.
• W2013502079 cites W2121237571 @default.
• W2013502079 cites W2123811191 @default.
• W2013502079 cites W2126143811 @default.
• W2013502079 cites W2135487462 @default.
• W2013502079 cites W2138106560 @default.
• W2013502079 cites W2139775379 @default.
• W2013502079 cites W2157902273 @default.
• W2013502079 cites W2162530578 @default.
• W2013502079 cites W2166095000 @default.
• W2013502079 cites W2170684975 @default.
• W2013502079 cites W2326848859 @default.
• W2013502079 cites W4254498040 @default.
• W2013502079 cites W4376453870 @default.
• W2013502079 doi "https://doi.org/10.1002/da.20628" @default.
• W2013502079 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2783721" @default.
• W2013502079 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19842164" @default.
• W2013502079 hasPublicationYear "2009" @default.
• W2013502079 type Work @default.
• W2013502079 sameAs 2013502079 @default.
• W2013502079 citedByCount "18" @default.
• W2013502079 countsByYear W20135020792012 @default.
• W2013502079 countsByYear W20135020792013 @default.
• W2013502079 countsByYear W20135020792014 @default.
• W2013502079 countsByYear W20135020792016 @default.
• W2013502079 countsByYear W20135020792017 @default.
• W2013502079 countsByYear W20135020792018 @default.
• W2013502079 countsByYear W20135020792020 @default.
• W2013502079 countsByYear W20135020792021 @default.
• W2013502079 countsByYear W20135020792022 @default.
• W2013502079 countsByYear W20135020792023 @default.
• W2013502079 crossrefType "journal-article" @default.
• W2013502079 hasAuthorship W2013502079A5008171523 @default.
• W2013502079 hasAuthorship W2013502079A5011961838 @default.
• W2013502079 hasAuthorship W2013502079A5019911642 @default.
• W2013502079 hasAuthorship W2013502079A5027640245 @default.
• W2013502079 hasAuthorship W2013502079A5044019481 @default.
• W2013502079 hasAuthorship W2013502079A5049231102 @default.
• W2013502079 hasAuthorship W2013502079A5050191788 @default.
• W2013502079 hasBestOaLocation W20135020792 @default.
• W2013502079 hasConcept C104317684 @default.
• W2013502079 hasConcept C118552586 @default.
• W2013502079 hasConcept C135763542 @default.
• W2013502079 hasConcept C139719470 @default.
• W2013502079 hasConcept C153209595 @default.
• W2013502079 hasConcept C15744967 @default.
• W2013502079 hasConcept C161890455 @default.
• W2013502079 hasConcept C162324750 @default.
• W2013502079 hasConcept C169594400 @default.
• W2013502079 hasConcept C186413461 @default.
• W2013502079 hasConcept C187288502 @default.
• W2013502079 hasConcept C2776317618 @default.
• W2013502079 hasConcept C2776867660 @default.
• W2013502079 hasConcept C2908647359 @default.
• W2013502079 hasConcept C54355233 @default.
• W2013502079 hasConcept C558461103 @default.
• W2013502079 hasConcept C60644358 @default.
• W2013502079 hasConcept C70410870 @default.
• W2013502079 hasConcept C71924100 @default.
• W2013502079 hasConcept C77805123 @default.
• W2013502079 hasConcept C86803240 @default.
• W2013502079 hasConcept C94612546 @default.
• W2013502079 hasConcept C99454951 @default.
• W2013502079 hasConceptScore W2013502079C104317684 @default.

• next