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• W2013529525 abstract "A theoretical treatment of single-file ion transport across pore-like channels in biological membranes is given. The unidirectional fluxes and the reversal potential are calculated. The interactions between the unidirectional fluxes are taken into account. Further, the blocking effects in the single-file pore-like channels and Coulomb effects between transported ions are included in the model. The model suggests that the energetical profile of the ion in the channel varies with the ion population in the channel. The presence of fixed anion in the selective region in the channel was suggested to form the additional potential well by splitting the selective barrier. It was shown that two-particle states of the channel which have the less probability than one-particle states due to Coulomb interactions can remarkably contribute the unidirectional fluxes. The comparison with the experimental data is given. New interpretation of selectivity is proposed. The calculation was based on graph theory. The perturbation theory in graph method was developed and used in the paper." @default.
• W2013529525 created "2016-06-24" @default.
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• W2013529525 date "1977-02-01" @default.
• W2013529525 modified "2023-09-27" @default.
• W2013529525 title "Ion transport across sodium channels in biological membranes" @default.
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• W2013529525 doi "https://doi.org/10.1016/0022-5193(77)90281-8" @default.
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