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• W2013573934 abstract "A structure-activity relationship study on polyamine derivatives led to the synthesis and the determination of antikinetoplastid activity of 17 compounds. Among them, a spermidine derivative (compound 13) was specifically active in vitro against Leishmania donovani axenic amastigotes (IC50 at 5.4μM; Selectivity Index >18.5) and a spermine derivative (compound 28) specifically active against Trypanosoma brucei gambiense (IC50 at 1.9μM; Selectivity Index >52)." @default.
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• W2013573934 date "2015-01-01" @default.
• W2013573934 modified "2023-10-14" @default.
• W2013573934 title "Design, synthesis and in vitro antikinetoplastid evaluation of N-acylated putrescine, spermidine and spermine derivatives" @default.
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• W2013573934 doi "https://doi.org/10.1016/j.bmcl.2014.11.073" @default.
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