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• W2013600241 abstract "DR DELBANCO: Mr C is a 48-year-old man with a long history of cognitive and psychological problems, marked by mood swings, memory loss, and seizures involving the frontal and temporal lobes of the brain. A primary physician, a neurologist with special interest in seizures (Dr J), and a psychiatrist (Dr N) manage Mr C’s care. He has private insurance, works part-time, and lives near Boston with his wife. Mr C’s problems likely date to birth. He was the product of an uncomplicated pregnancy but during labor there may have been some anoxia. He recalls a “foggy feeling” in his head from the first time he can remember. As a child, he fell out of a tree and hit his head without notable sequelae. In elementary school, he did well but had difficulty with his memory. He continued a successful academic experience in high school, during which time he had intermittent abdominal pains, and then was graduated from a top university with extraordinarily high academic achievement. In college, he describes having had difficulty understanding lectures and remembering details. He read avidly and worked endless hours but felt his ability to learn was hampered by a poor memory. He had difficulty handling several different tasks at once. In graduate school, depression because of his struggles with his cognitive limitations led to a suicide attempt, which caused a contusion to the right side of the head. Thereafter, Mr C was hospitalized; lithium followed by carbamazepine and phenytoin gave him more, but not complete, control of his symptoms. Neurologic evaluation at that time showed no persistent physical findings or lateralization. He was ambidextrous, and his right hand was noted to be a bit smaller than his left. Reflexes were diminished but bilaterally symmetrical. There were no motor or sensory findings. Multiple electroencephalogram (EEG), magnetic resonance imaging (MRI), computed tomography (CT), and positron emission tomography (PET) evaluations showed inconsistent findings. There were no clear ictal patterns on EEG. Over the next years, he was treated with multiple medications. Multiple MRI, CT, and PET scans, along with serial EEGs, continued to show inconsistent findings, with frequent abnormalities identified in the left frontal and temporal lobes. Mr C fared increasingly better, working at various jobs and getting married, until serious cognitive and affective disruption again supervened. Multiple high-dose antidepressants, augmentation strategies, neuroleptics, and atypical neuroleptics were tried without effect. However, over a period of several years, his mood and functionality slowly improved. In recent years, Mr C has worked part-time in jobs far less demanding than his superior intellectual attainment might otherwise anticipate. In 2000, Mr C contemplated surgery for possible focal epileptiform lesions in the brain, but depth electrode investigation revealed abnormalities that were multifocal and involved the anterior cingulate and supplementary motor areas. The abnormalities were more active on the left than on the right. He also had a left temporal lobe slow wave focus. Electrical stimulation through the left supplementary motor area electrode at subseizure threshold levels elicited his characteristic paroxysmal, seizurelike cognitive and affective symptoms. In addition to seizures, Mr C notes very poor memory, which has led to great difficulty in recognizing people and has put him in awkward social circumstances on many occasions. A talented musician, Mr C plays an instrument with considerable competence but has great difficulty remembering pieces even after extensive practice. He feels worse during the winter months and notes that lack of sleep exacerbates the symptoms that are likely partial seizures. Sexual activity at times exacerbates his symptoms. He notes also long-standing tinnitus in the right ear, with a sense of white noise coming from his left ear. During seizure activity, he feels he is spinning backward in space and that his limbs become very long. For decades, Mr C developed an intermittent rash on his right arm, and recent evaluation demonstrated herpes simplex virus 2 infection. Appearance of the eruption appears to coincide with exacerbations of his seizures, and, in the" @default.
• W2013600241 created "2016-06-24" @default.
• W2013600241 creator A5001041177 @default.
• W2013600241 date "2003-07-16" @default.
• W2013600241 modified "2023-09-25" @default.
• W2013600241 title "A 48-Year-Old Man With Temporal Lobe Epilepsy and Psychiatric Illness" @default.
• W2013600241 cites W1531376978 @default.
• W2013600241 cites W1573130913 @default.
• W2013600241 cites W1595103669 @default.
• W2013600241 cites W177658873 @default.
• W2013600241 cites W1841029273 @default.
• W2013600241 cites W1847881638 @default.
• W2013600241 cites W1860410442 @default.
• W2013600241 cites W1964785025 @default.
• W2013600241 cites W1967331310 @default.
• W2013600241 cites W1974809694 @default.
• W2013600241 cites W1974874458 @default.
• W2013600241 cites W1977013974 @default.
• W2013600241 cites W1977691108 @default.
• W2013600241 cites W1980525228 @default.
• W2013600241 cites W1982034579 @default.
• W2013600241 cites W1984492957 @default.
• W2013600241 cites W1985394452 @default.
• W2013600241 cites W1985667706 @default.
• W2013600241 cites W1985885181 @default.
• W2013600241 cites W1985964054 @default.
• W2013600241 cites W1993118024 @default.
• W2013600241 cites W2002336714 @default.
• W2013600241 cites W2015208865 @default.
• W2013600241 cites W2017040969 @default.
• W2013600241 cites W2018493160 @default.
• W2013600241 cites W2019591247 @default.
• W2013600241 cites W2021459081 @default.
• W2013600241 cites W2024116892 @default.
• W2013600241 cites W2027512306 @default.
• W2013600241 cites W2036864487 @default.
• W2013600241 cites W2037306742 @default.
• W2013600241 cites W2037647952 @default.
• W2013600241 cites W2041093905 @default.
• W2013600241 cites W2044452957 @default.
• W2013600241 cites W2044834902 @default.
• W2013600241 cites W2047532687 @default.
• W2013600241 cites W2047678058 @default.
• W2013600241 cites W2047917340 @default.
• W2013600241 cites W2048424859 @default.
• W2013600241 cites W2049277385 @default.
• W2013600241 cites W2049845264 @default.
• W2013600241 cites W2059560616 @default.
• W2013600241 cites W2071318202 @default.
• W2013600241 cites W2075851334 @default.
• W2013600241 cites W2078371419 @default.
• W2013600241 cites W2078694029 @default.
• W2013600241 cites W2079878675 @default.
• W2013600241 cites W2080762052 @default.
• W2013600241 cites W2086132039 @default.
• W2013600241 cites W2086935208 @default.
• W2013600241 cites W2109176867 @default.
• W2013600241 cites W2113407406 @default.
• W2013600241 cites W2113828118 @default.
• W2013600241 cites W2121587872 @default.
• W2013600241 cites W2129216136 @default.
• W2013600241 cites W2130853198 @default.
• W2013600241 cites W2132239248 @default.
• W2013600241 cites W2150414630 @default.
• W2013600241 cites W2153134014 @default.
• W2013600241 cites W2158433702 @default.
• W2013600241 cites W2159826847 @default.
• W2013600241 cites W2172178327 @default.
• W2013600241 cites W2172251415 @default.
• W2013600241 cites W2179708255 @default.
• W2013600241 cites W2237028671 @default.
• W2013600241 cites W2317495993 @default.
• W2013600241 cites W2320058521 @default.
• W2013600241 cites W2327262353 @default.
• W2013600241 cites W2338591783 @default.
• W2013600241 cites W2341052426 @default.
• W2013600241 cites W2349841094 @default.
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• W2013600241 cites W2400355621 @default.
• W2013600241 cites W2440035543 @default.
• W2013600241 cites W2442539006 @default.
• W2013600241 cites W332441138 @default.
• W2013600241 cites W338219220 @default.
• W2013600241 cites W45745623 @default.
• W2013600241 cites W53451209 @default.
• W2013600241 cites W2043215706 @default.
• W2013600241 cites W2488375416 @default.
• W2013600241 doi "https://doi.org/10.1001/jama.290.3.381" @default.
• W2013600241 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12865380" @default.
• W2013600241 hasPublicationYear "2003" @default.
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