Matches in SemOpenAlex for { <https://semopenalex.org/work/W2013600541> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2013600541 endingPage "127" @default.
- W2013600541 startingPage "124" @default.
- W2013600541 abstract "Isolated trisomy 2 in hematopoietic malignancies is rare, having been reported in only eight cases. Of these cases, the majority are older males. The underlying hematologic malignancies range from myelodysplastic syndrome (MDS) to acute myeloid leukemia (AML). The molecular pathogenesis and prognostic significance of isolated trisomy 2 remains unknown. Herein, we report 11 cases of isolated trisomy 2 in hematologic disorders seen in the Mayo Clinic Cytogenetics laboratory from 1996-2012. The majority were older males between the ages of 63-93 years. The underlying bone marrow pathologic diagnoses ranged from no diagnostic features of malignancy to AML. Our data suggest that isolated trisomy 2 could represent an age-related phenomenon since all 11 cases were age 63 and over. It appears that isolated trisomy 2 harbors little prognostic significance and that, instead, the prognostic significance is driven by the underlying pathologic diagnosis. For example, whereas 3 of the cases with AML survived only 7-10 weeks post-bone marrow biopsy, 1 of the cases without diagnostic features of malignancy survived 10 additional years. Therefore, trisomy 2 as a sole abnormality should not be considered as definitive evidence for a myeloid neoplasm in the absence of diagnostic morphologic criteria." @default.
- W2013600541 created "2016-06-24" @default.
- W2013600541 creator A5060532068 @default.
- W2013600541 creator A5065115486 @default.
- W2013600541 creator A5082478466 @default.
- W2013600541 creator A5084686872 @default.
- W2013600541 date "2014-04-01" @default.
- W2013600541 modified "2023-09-23" @default.
- W2013600541 title "Isolated trisomy 2 in bone marrows of patients with suspected hematopoietic malignancies" @default.
- W2013600541 cites W1605230984 @default.
- W2013600541 cites W1965946975 @default.
- W2013600541 cites W1968030407 @default.
- W2013600541 cites W1984227416 @default.
- W2013600541 cites W2062126915 @default.
- W2013600541 cites W2089637793 @default.
- W2013600541 cites W2090031882 @default.
- W2013600541 cites W2912915821 @default.
- W2013600541 cites W2131558552 @default.
- W2013600541 doi "https://doi.org/10.1016/j.cancergen.2014.02.011" @default.
- W2013600541 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24736057" @default.
- W2013600541 hasPublicationYear "2014" @default.
- W2013600541 type Work @default.
- W2013600541 sameAs 2013600541 @default.
- W2013600541 citedByCount "0" @default.
- W2013600541 crossrefType "journal-article" @default.
- W2013600541 hasAuthorship W2013600541A5060532068 @default.
- W2013600541 hasAuthorship W2013600541A5065115486 @default.
- W2013600541 hasAuthorship W2013600541A5082478466 @default.
- W2013600541 hasAuthorship W2013600541A5084686872 @default.
- W2013600541 hasConcept C104317684 @default.
- W2013600541 hasConcept C126322002 @default.
- W2013600541 hasConcept C142724271 @default.
- W2013600541 hasConcept C174475383 @default.
- W2013600541 hasConcept C2776229224 @default.
- W2013600541 hasConcept C2778729363 @default.
- W2013600541 hasConcept C2779399171 @default.
- W2013600541 hasConcept C2779672484 @default.
- W2013600541 hasConcept C2780007613 @default.
- W2013600541 hasConcept C2780365373 @default.
- W2013600541 hasConcept C2780817109 @default.
- W2013600541 hasConcept C2909984355 @default.
- W2013600541 hasConcept C30481170 @default.
- W2013600541 hasConcept C54355233 @default.
- W2013600541 hasConcept C63363279 @default.
- W2013600541 hasConcept C71924100 @default.
- W2013600541 hasConcept C86803240 @default.
- W2013600541 hasConceptScore W2013600541C104317684 @default.
- W2013600541 hasConceptScore W2013600541C126322002 @default.
- W2013600541 hasConceptScore W2013600541C142724271 @default.
- W2013600541 hasConceptScore W2013600541C174475383 @default.
- W2013600541 hasConceptScore W2013600541C2776229224 @default.
- W2013600541 hasConceptScore W2013600541C2778729363 @default.
- W2013600541 hasConceptScore W2013600541C2779399171 @default.
- W2013600541 hasConceptScore W2013600541C2779672484 @default.
- W2013600541 hasConceptScore W2013600541C2780007613 @default.
- W2013600541 hasConceptScore W2013600541C2780365373 @default.
- W2013600541 hasConceptScore W2013600541C2780817109 @default.
- W2013600541 hasConceptScore W2013600541C2909984355 @default.
- W2013600541 hasConceptScore W2013600541C30481170 @default.
- W2013600541 hasConceptScore W2013600541C54355233 @default.
- W2013600541 hasConceptScore W2013600541C63363279 @default.
- W2013600541 hasConceptScore W2013600541C71924100 @default.
- W2013600541 hasConceptScore W2013600541C86803240 @default.
- W2013600541 hasIssue "4" @default.
- W2013600541 hasLocation W20136005411 @default.
- W2013600541 hasLocation W20136005412 @default.
- W2013600541 hasOpenAccess W2013600541 @default.
- W2013600541 hasPrimaryLocation W20136005411 @default.
- W2013600541 hasRelatedWork W162419245 @default.
- W2013600541 hasRelatedWork W1931461250 @default.
- W2013600541 hasRelatedWork W1980258848 @default.
- W2013600541 hasRelatedWork W2029022019 @default.
- W2013600541 hasRelatedWork W2040420871 @default.
- W2013600541 hasRelatedWork W2045323835 @default.
- W2013600541 hasRelatedWork W2128802365 @default.
- W2013600541 hasRelatedWork W2435909417 @default.
- W2013600541 hasRelatedWork W35686571 @default.
- W2013600541 hasRelatedWork W2084624487 @default.
- W2013600541 hasVolume "207" @default.
- W2013600541 isParatext "false" @default.
- W2013600541 isRetracted "false" @default.
- W2013600541 magId "2013600541" @default.
- W2013600541 workType "article" @default.