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- W2013622479 abstract "The actions of excitatory amino acid agonists and antagonists on rod driven horizontal cells were studied in the isolated retina of the rat. Horizontal cells were depolarised by L-glutamate, kainate and quisqualate but not by N-methyl-D-aspartate (NMDA). The broad band excitatory amino acid antagonist, kynurenate and the non-NMDA antagonist, 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX), hyperpolarised horizontal cells, blocking the light responses and also the effects of agonists. In contrast, the competitive NMDA antagonists, 3-[(+/-)-2-carboxypiperazin-4-yl]-propyl-1-phosphonate (CPP) and 2-amino-5-phosphono-pentanoate (AP5) were without effect. Thus, rat horizontal cells possess excitatory amino acid receptors of the non-NMDA type and these mediate their rod driven inputs." @default.
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- W2013622479 date "1991-01-01" @default.
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- W2013622479 title "Non-NMDA type excitatory amino acid receptors mediate rod input to horizontal cells in the isolated rat retina" @default.
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- W2013622479 doi "https://doi.org/10.1016/0042-6989(91)90001-l" @default.
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