FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2013639959> ?p ?o ?g. }

• W2013639959 endingPage "616" @default.
• W2013639959 startingPage "606" @default.
• W2013639959 abstract "Abstract Few population‐based case‐control studies have assessed etiologic factors for penile cancer. Past infection with high‐risk human papillomavirus (HPV) is a known risk factor for penile cancer; however, few previous studies have related the HPV DNA status of the tumor to potential demographic and behavioral risk factors for the disease or evaluated whether in situ and invasive penile cancer share risk factors. Little information is available on the role and timing of circumcision in the etiology of penile cancer. We conducted a population‐based case‐control study in western Washington state that included 137 men diagnosed with in situ ( n = 75) or invasive ( n = 62) penile cancer between January 1, 1979, and December 31, 1998, and 671 control men identified through random digit dialing. Cases and controls were interviewed in person and provided peripheral blood samples. Case and control blood samples were tested for antibodies to HPV16 and HSV‐2, and tumor specimens from cases were tested for HPV DNA. Men not circumcised during childhood were at increased risk of invasive (OR = 2.3, 95% CI 1.3–4.1) but not in situ (OR = 1.1, 95% CI 0.6–1.8) penile cancer. Approximately 35% of men with penile cancer who had not been circumcised in childhood reported a history of phimosis compared to 7.6% of controls (OR = 7.4, 95% CI 3.7–15.0). Penile conditions such as tear, rash and injury were associated with increased risk of disease. Among men not circumcised in childhood, phimosis was strongly associated with development of invasive penile cancer (OR = 11.4, 95% CI 5.0–25.9). When we restricted our analysis to men who did not have phimosis, the risk of invasive penile cancer associated with not having been circumcised in childhood was not elevated (OR = 0.5, 95% CI 0.1–2.5). Cigarette smoking was associated with a 4.5‐fold risk (95% CI 2.0–10.1) of invasive penile cancer. HPV DNA was detected in 79.8% of tumor specimens, and 69.1% of tumors were HPV16‐positive. The proportion of HPV DNA‐positive tumors did not vary by any risk factors evaluated. Many risk factors were common for both in situ and invasive disease. However, 3 factors that did not increase the risk for in situ cancer proved significant risk factors for invasive penile cancer: lack of circumcision during childhood, phimosis and cigarette smoking. The high percentage of HPV DNA‐positive tumors in our study is consistent with a strong association between HPV infection and the development of penile cancer regardless of circumcision status. Circumcision in early childhood may help prevent penile cancer by eliminating phimosis, a significant risk factor for the disease. © 2005 Wiley‐Liss, Inc." @default.
• W2013639959 created "2016-06-24" @default.
• W2013639959 creator A5005110444 @default.
• W2013639959 creator A5006512142 @default.
• W2013639959 creator A5013624819 @default.
• W2013639959 creator A5016769319 @default.
• W2013639959 creator A5033491530 @default.
• W2013639959 creator A5035683753 @default.
• W2013639959 creator A5060678439 @default.
• W2013639959 creator A5089601078 @default.
• W2013639959 creator A5090963692 @default.
• W2013639959 creator A5091170830 @default.
• W2013639959 creator A5091846363 @default.
• W2013639959 date "2005-04-11" @default.
• W2013639959 modified "2023-10-17" @default.
• W2013639959 title "Penile cancer: Importance of circumcision, human papillomavirus and smoking inin situ and invasive disease" @default.
• W2013639959 cites W134002511 @default.
• W2013639959 cites W1965037168 @default.
• W2013639959 cites W1985046870 @default.
• W2013639959 cites W1988433879 @default.
• W2013639959 cites W1995758864 @default.
• W2013639959 cites W2023347252 @default.
• W2013639959 cites W2025841318 @default.
• W2013639959 cites W2027756249 @default.
• W2013639959 cites W2040031103 @default.
• W2013639959 cites W2052859771 @default.
• W2013639959 cites W2082308035 @default.
• W2013639959 cites W2085234632 @default.
• W2013639959 cites W2085813472 @default.
• W2013639959 cites W2090700235 @default.
• W2013639959 cites W2117995803 @default.
• W2013639959 cites W2168583660 @default.
• W2013639959 doi "https://doi.org/10.1002/ijc.21009" @default.
• W2013639959 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15825185" @default.
• W2013639959 hasPublicationYear "2005" @default.
• W2013639959 type Work @default.
• W2013639959 sameAs 2013639959 @default.
• W2013639959 citedByCount "406" @default.
• W2013639959 countsByYear W20136399592012 @default.
• W2013639959 countsByYear W20136399592013 @default.
• W2013639959 countsByYear W20136399592014 @default.
• W2013639959 countsByYear W20136399592015 @default.
• W2013639959 countsByYear W20136399592016 @default.
• W2013639959 countsByYear W20136399592017 @default.
• W2013639959 countsByYear W20136399592018 @default.
• W2013639959 countsByYear W20136399592019 @default.
• W2013639959 countsByYear W20136399592020 @default.
• W2013639959 countsByYear W20136399592021 @default.
• W2013639959 countsByYear W20136399592022 @default.
• W2013639959 countsByYear W20136399592023 @default.
• W2013639959 crossrefType "journal-article" @default.
• W2013639959 hasAuthorship W2013639959A5005110444 @default.
• W2013639959 hasAuthorship W2013639959A5006512142 @default.
• W2013639959 hasAuthorship W2013639959A5013624819 @default.
• W2013639959 hasAuthorship W2013639959A5016769319 @default.
• W2013639959 hasAuthorship W2013639959A5033491530 @default.
• W2013639959 hasAuthorship W2013639959A5035683753 @default.
• W2013639959 hasAuthorship W2013639959A5060678439 @default.
• W2013639959 hasAuthorship W2013639959A5089601078 @default.
• W2013639959 hasAuthorship W2013639959A5090963692 @default.
• W2013639959 hasAuthorship W2013639959A5091170830 @default.
• W2013639959 hasAuthorship W2013639959A5091846363 @default.
• W2013639959 hasBestOaLocation W20136399591 @default.
• W2013639959 hasConcept C121608353 @default.
• W2013639959 hasConcept C126322002 @default.
• W2013639959 hasConcept C137627325 @default.
• W2013639959 hasConcept C146304588 @default.
• W2013639959 hasConcept C2777180808 @default.
• W2013639959 hasConcept C2778220009 @default.
• W2013639959 hasConcept C2908647359 @default.
• W2013639959 hasConcept C29456083 @default.
• W2013639959 hasConcept C50440223 @default.
• W2013639959 hasConcept C71924100 @default.
• W2013639959 hasConcept C99454951 @default.
• W2013639959 hasConceptScore W2013639959C121608353 @default.
• W2013639959 hasConceptScore W2013639959C126322002 @default.
• W2013639959 hasConceptScore W2013639959C137627325 @default.
• W2013639959 hasConceptScore W2013639959C146304588 @default.
• W2013639959 hasConceptScore W2013639959C2777180808 @default.
• W2013639959 hasConceptScore W2013639959C2778220009 @default.
• W2013639959 hasConceptScore W2013639959C2908647359 @default.
• W2013639959 hasConceptScore W2013639959C29456083 @default.
• W2013639959 hasConceptScore W2013639959C50440223 @default.
• W2013639959 hasConceptScore W2013639959C71924100 @default.
• W2013639959 hasConceptScore W2013639959C99454951 @default.
• W2013639959 hasIssue "4" @default.
• W2013639959 hasLocation W20136399591 @default.
• W2013639959 hasLocation W20136399592 @default.
• W2013639959 hasOpenAccess W2013639959 @default.
• W2013639959 hasPrimaryLocation W20136399591 @default.
• W2013639959 hasRelatedWork W13949714 @default.
• W2013639959 hasRelatedWork W1988937944 @default.
• W2013639959 hasRelatedWork W2016390559 @default.
• W2013639959 hasRelatedWork W2019481302 @default.
• W2013639959 hasRelatedWork W2033020705 @default.
• W2013639959 hasRelatedWork W2100442783 @default.
• W2013639959 hasRelatedWork W2120270011 @default.
• W2013639959 hasRelatedWork W3119922967 @default.

• next