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- W2013647553 abstract "Abstract The effect on cytotoxicity of in vitro incubation of lymphocytes (L) and monocytemacrophages (MP) for 2 h or 24 h, either together (unseparated) or separated, was examined. The yield of MP decreased with prolonged incubation while similar numbers of viable L were obtained with 2 h and 24 h incubation. L and MP spontaneous cytotoxicity (SCT) declined with prolonged incubation. L ADCC increased after 24 h incubation of separated and unseparated cells. In contrast, MP ADCC increased only after incubation of L and MP together and not when MP were incubated separately for 24 h. These data support the hypothesis that circulating MP ADCC effector cells, and possibly L ADCC effector cells, are functionally immature, and by interaction with non-adherent mononuclear cells can be made more active or more numerous." @default.
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- W2013647553 date "1978-12-01" @default.
- W2013647553 modified "2023-09-25" @default.
- W2013647553 title "Comparison of cytotoxicity mediated by human monocyte-macrophages and lymphocytes after prolonged in vitro incubation" @default.
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- W2013647553 doi "https://doi.org/10.1016/0022-1759(78)90137-0" @default.
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