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- W2013660177 endingPage "240" @default.
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- W2013660177 abstract "Information accumulated in recent years has begun to unveil a previously unsuspected complexity in the innervation of the lungs. We know now that the conducting airways receive a highly redundant supply of vagal motor and sensory fibers; that many of these fibers cross over from the contralateral side of the brain to reach distant portions of the lung, thereby assuring the symmetry and simultaneity of the bronchomotor responses; and that, perhaps in recognition of the different functions and properties of proximal and distal airways, vagal motor fibers have a distinctive segmental distribution. Both sensory and motor neurons serve as the input and output elements of a complex brain stem neuronal network, which integrates the regulation of airway smooth muscle tone into the control of ventilation. This network has a local counterpart in the airway walls, where a heterogeneous population of intrinsic neurons may act not only as a relay for cholinergic stimuli, but also as a local mechanism of inflammatory modulation. The interruption of the nerve supply to the lungs (for instance after lung transplantation) abolishes the integration of bronchomotor and ventilatory activities, and, by increasing airway deformation, may initiate fibroproliferative responses in the airway walls. In addition, the destruction of vagal motor and sensory fibers leaves behind a surviving population of denervated intrinsic neurons, which may act as a disregulated mechanism of inflammatory amplification." @default.
- W2013660177 created "2016-06-24" @default.
- W2013660177 creator A5084687045 @default.
- W2013660177 date "2002-01-01" @default.
- W2013660177 modified "2023-10-14" @default.
- W2013660177 title "On lung nerves and neurogenic injury" @default.
- W2013660177 cites W1554043067 @default.
- W2013660177 cites W1788732318 @default.
- W2013660177 cites W1879993508 @default.
- W2013660177 cites W1909704625 @default.
- W2013660177 cites W1911892500 @default.
- W2013660177 cites W1964328050 @default.
- W2013660177 cites W1968544303 @default.
- W2013660177 cites W1971632936 @default.
- W2013660177 cites W1974172485 @default.
- W2013660177 cites W1980037780 @default.
- W2013660177 cites W1980383565 @default.
- W2013660177 cites W1982127469 @default.
- W2013660177 cites W1983933746 @default.
- W2013660177 cites W1984617938 @default.
- W2013660177 cites W1984741208 @default.
- W2013660177 cites W1988593402 @default.
- W2013660177 cites W1991881272 @default.
- W2013660177 cites W1993265357 @default.
- W2013660177 cites W1994075163 @default.
- W2013660177 cites W1995682943 @default.
- W2013660177 cites W1998655325 @default.
- W2013660177 cites W2000654130 @default.
- W2013660177 cites W2003100003 @default.
- W2013660177 cites W2007860313 @default.
- W2013660177 cites W2010784234 @default.
- W2013660177 cites W2012272559 @default.
- W2013660177 cites W2012609425 @default.
- W2013660177 cites W2014195246 @default.
- W2013660177 cites W201615939 @default.
- W2013660177 cites W2016431526 @default.
- W2013660177 cites W2016919586 @default.
- W2013660177 cites W2019562281 @default.
- W2013660177 cites W2025592913 @default.
- W2013660177 cites W2026403230 @default.
- W2013660177 cites W2029373941 @default.
- W2013660177 cites W2032860070 @default.
- W2013660177 cites W2034198619 @default.
- W2013660177 cites W2037351441 @default.
- W2013660177 cites W2038857990 @default.
- W2013660177 cites W2041185198 @default.
- W2013660177 cites W2041820521 @default.
- W2013660177 cites W2041986290 @default.
- W2013660177 cites W2044047233 @default.
- W2013660177 cites W2044520352 @default.
- W2013660177 cites W2047920764 @default.
- W2013660177 cites W2048228896 @default.
- W2013660177 cites W2049282428 @default.
- W2013660177 cites W2050158026 @default.
- W2013660177 cites W2050470946 @default.
- W2013660177 cites W2050578748 @default.
- W2013660177 cites W2050792388 @default.
- W2013660177 cites W2053672287 @default.
- W2013660177 cites W2058702729 @default.
- W2013660177 cites W2061119197 @default.
- W2013660177 cites W2063825262 @default.
- W2013660177 cites W2064079119 @default.
- W2013660177 cites W2069028709 @default.
- W2013660177 cites W2072051059 @default.
- W2013660177 cites W2073645604 @default.
- W2013660177 cites W2076439215 @default.
- W2013660177 cites W2080505208 @default.
- W2013660177 cites W2081579581 @default.
- W2013660177 cites W2081839806 @default.
- W2013660177 cites W2085128865 @default.
- W2013660177 cites W2092912965 @default.
- W2013660177 cites W2093531619 @default.
- W2013660177 cites W2094229658 @default.
- W2013660177 cites W2096591034 @default.
- W2013660177 cites W2119254984 @default.
- W2013660177 cites W2129108051 @default.
- W2013660177 cites W2136349426 @default.
- W2013660177 cites W2139683890 @default.
- W2013660177 cites W2140133657 @default.
- W2013660177 cites W2144896326 @default.
- W2013660177 cites W2149202300 @default.
- W2013660177 cites W2149722797 @default.
- W2013660177 cites W2181478676 @default.
- W2013660177 cites W2186825337 @default.
- W2013660177 cites W2291591405 @default.
- W2013660177 cites W2294681141 @default.
- W2013660177 cites W2341123437 @default.
- W2013660177 cites W2341267780 @default.
- W2013660177 cites W2415686408 @default.
- W2013660177 cites W2419023089 @default.
- W2013660177 cites W2422321485 @default.
- W2013660177 cites W2470731951 @default.
- W2013660177 cites W4253446802 @default.
- W2013660177 doi "https://doi.org/10.1080/078538902320322493" @default.
- W2013660177 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12371707" @default.
- W2013660177 hasPublicationYear "2002" @default.
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