FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2013663311> ?p ?o ?g. }

• W2013663311 endingPage "230" @default.
• W2013663311 startingPage "223" @default.
• W2013663311 abstract "The central nervous system (CNS) possesses a well-known capacity for circuitry rearrangement, or “plasticity,” which is maintained throughout life. Two well-studied categories of CNS plasticity are the circuitry rearrangement which occurs in response to injury and that which occurs in response to normal environmental stimuli. In an injury response, such as that which follows partial denervation of the hippocampus by unilateral removal of the entorhinal cortex, undamaged fibers in the denervated zone sprout and form new connections to replace lost synapses. In addition, rearrangement of circuitry also takes place in nondenervated zones which are functionally associated with the denervated circuitry. These observations indicate that the CNS is capable of major remodeling of neuronal circuitry, both in response to an injury as well as in the absence of a direct insult. Importantly, such plasticity reactions after injury appear to mediate recovery of lost function in hippocampal-dependent learning. Plasticity can also occur in response to relatively subtle stimuli, such as are found in an enriched environment or with exercise. Even tightly structured repetitive exercise, such as wheel-running by rats, drives plasticity responses in brain regions such as the hippocampus, cortex, and cerebellum. Plasticity in response to injury and environmentally driven plasticity share similar molecular features, such as activation of growth factors, suggesting that some molecular events and mechanisms driving circuitry remodeling are common to all forms of plasticity. In this review, these two categories of CNS plasticity are discussed, using in vivo models to illustrate remodeling occurring after damage, as well as environmentally driven plasticity. MRDD Research Reviews 1998; 4:223–230 © 1998 Wiley-Liss, Inc." @default.
• W2013663311 created "2016-06-24" @default.
• W2013663311 creator A5006246066 @default.
• W2013663311 creator A5059339971 @default.
• W2013663311 date "1998-01-01" @default.
• W2013663311 modified "2023-09-24" @default.
• W2013663311 title "Plasticity and growth factors in injury response" @default.
• W2013663311 cites W1572339786 @default.
• W2013663311 cites W1647778121 @default.
• W2013663311 cites W1897632924 @default.
• W2013663311 cites W1918871866 @default.
• W2013663311 cites W1965448417 @default.
• W2013663311 cites W1970516662 @default.
• W2013663311 cites W1975992615 @default.
• W2013663311 cites W1977311786 @default.
• W2013663311 cites W1984200333 @default.
• W2013663311 cites W1990645591 @default.
• W2013663311 cites W1995518019 @default.
• W2013663311 cites W2001123589 @default.
• W2013663311 cites W2004469687 @default.
• W2013663311 cites W2008176893 @default.
• W2013663311 cites W2009218414 @default.
• W2013663311 cites W2009490317 @default.
• W2013663311 cites W2009742165 @default.
• W2013663311 cites W2010856791 @default.
• W2013663311 cites W2011007038 @default.
• W2013663311 cites W2024570545 @default.
• W2013663311 cites W2027110288 @default.
• W2013663311 cites W2028792291 @default.
• W2013663311 cites W2033027472 @default.
• W2013663311 cites W2037763141 @default.
• W2013663311 cites W2048329982 @default.
• W2013663311 cites W2050992850 @default.
• W2013663311 cites W2054649340 @default.
• W2013663311 cites W2056422991 @default.
• W2013663311 cites W2058479911 @default.
• W2013663311 cites W2063581443 @default.
• W2013663311 cites W2065009470 @default.
• W2013663311 cites W2069485678 @default.
• W2013663311 cites W2071280637 @default.
• W2013663311 cites W2072042335 @default.
• W2013663311 cites W2085631765 @default.
• W2013663311 cites W2093268225 @default.
• W2013663311 cites W2093311371 @default.
• W2013663311 cites W2116185710 @default.
• W2013663311 cites W2122331294 @default.
• W2013663311 cites W2133149481 @default.
• W2013663311 cites W2139723249 @default.
• W2013663311 cites W4238957406 @default.
• W2013663311 cites W43432051 @default.
• W2013663311 doi "https://doi.org/10.1002/(sici)1098-2779(1998)4:3<223::aid-mrdd10>3.0.co;2-x" @default.
• W2013663311 hasPublicationYear "1998" @default.
• W2013663311 type Work @default.
• W2013663311 sameAs 2013663311 @default.
• W2013663311 citedByCount "12" @default.
• W2013663311 crossrefType "journal-article" @default.
• W2013663311 hasAuthorship W2013663311A5006246066 @default.
• W2013663311 hasAuthorship W2013663311A5059339971 @default.
• W2013663311 hasConcept C105702510 @default.
• W2013663311 hasConcept C121332964 @default.
• W2013663311 hasConcept C148762608 @default.
• W2013663311 hasConcept C169760540 @default.
• W2013663311 hasConcept C170493617 @default.
• W2013663311 hasConcept C194973443 @default.
• W2013663311 hasConcept C2776805190 @default.
• W2013663311 hasConcept C2781161787 @default.
• W2013663311 hasConcept C47611674 @default.
• W2013663311 hasConcept C53927964 @default.
• W2013663311 hasConcept C55493867 @default.
• W2013663311 hasConcept C79186407 @default.
• W2013663311 hasConcept C86803240 @default.
• W2013663311 hasConcept C86878447 @default.
• W2013663311 hasConcept C97355855 @default.
• W2013663311 hasConcept C98229152 @default.
• W2013663311 hasConceptScore W2013663311C105702510 @default.
• W2013663311 hasConceptScore W2013663311C121332964 @default.
• W2013663311 hasConceptScore W2013663311C148762608 @default.
• W2013663311 hasConceptScore W2013663311C169760540 @default.
• W2013663311 hasConceptScore W2013663311C170493617 @default.
• W2013663311 hasConceptScore W2013663311C194973443 @default.
• W2013663311 hasConceptScore W2013663311C2776805190 @default.
• W2013663311 hasConceptScore W2013663311C2781161787 @default.
• W2013663311 hasConceptScore W2013663311C47611674 @default.
• W2013663311 hasConceptScore W2013663311C53927964 @default.
• W2013663311 hasConceptScore W2013663311C55493867 @default.
• W2013663311 hasConceptScore W2013663311C79186407 @default.
• W2013663311 hasConceptScore W2013663311C86803240 @default.
• W2013663311 hasConceptScore W2013663311C86878447 @default.
• W2013663311 hasConceptScore W2013663311C97355855 @default.
• W2013663311 hasConceptScore W2013663311C98229152 @default.
• W2013663311 hasIssue "3" @default.
• W2013663311 hasLocation W20136633111 @default.
• W2013663311 hasOpenAccess W2013663311 @default.
• W2013663311 hasPrimaryLocation W20136633111 @default.
• W2013663311 hasRelatedWork W13973986 @default.
• W2013663311 hasRelatedWork W1559117788 @default.
• W2013663311 hasRelatedWork W16671885 @default.
• W2013663311 hasRelatedWork W1825929091 @default.

• next