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- W2013663885 abstract "Abstract We describe a peptide fragment, solid-phase coupling strategy for synthesis of peptide-oligonucleotide conjugates. Model conjugates contained a hydrophobic tetrapeptide, a hydrophobic influenza virus fusion nonapeptide, or a basic octapeptide of the HIV-1 Tat protein coupled to either dT12 or a 16-mer anti-Tat oligodeoxyribonucleotide. Conjugation yields were improved by removal of internucleotide 2-cyanoethyl groups prior to peptide coupling and by use of a C12 spacer between peptide and oligonucleotide." @default.
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- W2013663885 date "1999-06-01" @default.
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- W2013663885 title "Studies Towards the Synthesis of Peptide-Oligonucleotide Conjugates" @default.
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- W2013663885 doi "https://doi.org/10.1080/07328319908044748" @default.
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