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- W2013668162 abstract "Fibromyalgia is a condition defined by chronic widespread pain and associated with central excitability and loss of descending inhibition. Pain associated with fibromyalgia interferes with daily function. TENS produces its effects primarily by reducing central excitability and activating descending inhibitory pathways. The primary objective of this study was to test the effect of TENS on pain, function and descending inhibition in people with fibromyalgia. The study used a crossover design of 43 Fibromyalgia patients (42F; 1M), aged 25-76 years (mean 49.2 ± 12.9yrs) with random assignment to three treatments: Active TENS (100 Hz, 200 μs), Placebo TENS and No Treatment Control. Pain was assessed with a visual analog scale (VAS) at rest and during the six minute walk test (6MWT) and pain sensitivity was assessed with pressure pain thresholds (PPT). Function was assessed with 6MWT at each session before/after TENS treatment. Descending inhibition was tested with foot ice water bath (4° C). Results indicated there was no difference in pain at rest between TENS conditions. However, there was a significant decrease in pain with movement (6MWT) for Active TENS compared to Placebo TENS (p ≤ .05) or No Treatment condition (p≤ .05). Further, there was increased distance walked (ft ± 41.85) in the 6MWT Active TENS group when compared to Placebo TENS (p≤.05) or No Treatment groups (p≤ .05). PPTs increased in the cervical region (p≤ .05) during Active TENS. During DNIC, changes in both PPT and pain intensity during the 6MWT (r2=0.4, p=0.02) were correlated with changes in PPT (r2=0.03, p=0.03) for active TENS but not Placebo or No treatment groups. Our data suggest that TENS reduces pain sensitivity, decreases pain during movement, improves function during routine walking and the DNIC response predicts the response to active TENS. Grant from the Orthopedic Section of the American Physical Therapy Association" @default.
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- W2013668162 date "2011-04-01" @default.
- W2013668162 modified "2023-09-25" @default.
- W2013668162 title "Transcutaneous Electrical Nerve Stimulation (TENS) reduces pain and improves function in people with Fibromyalgia" @default.
- W2013668162 doi "https://doi.org/10.1016/j.jpain.2011.02.091" @default.
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