Matches in SemOpenAlex for { <https://semopenalex.org/work/W2013672381> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2013672381 endingPage "37" @default.
- W2013672381 startingPage "32" @default.
- W2013672381 abstract "In progressive IgA-nephropathy (IgAN) no established therapy exists. We have analyzed the clinical course of 40 patients with progressive IgAN with tonsillectomy combined with cyclophosphamide (TE/CTX), high dose immunoglobulins (IVIG), or cyclophosphamide pulses (CyP), and 8 untreated patients as historical controls. Serum creatinine >250 micromol/l at beginning, proteinuria >2.5 g/l, and age >51 years were significant predictors for end stage renal failure in Cox regression analysis. In linear regression analysis, the decline of renal function significantly decreased only in patients after CyP from 29.7% per year to 2.8% per year. Proteinuria significantly decreased only in patients after CyP from 1.3 g/l to 1.1 g/l. IVIG had no maintained long term effect on renal function, and TE/CTX had no significant influence on renal function. In Kaplan Meier analysis, patients with CyP had a significantly higher cumulative probability of renal survival compared to the other patients. In conclusion, TE/CTX is not recommended in patients with advanced, progressive IgAN, if not surgically indicated. IVIG had no long-term effect on progression of IgAN. CyP therapy is able to stop the loss of renal function and decreases proteinuria in patients with progressive IgAN." @default.
- W2013672381 created "2016-06-24" @default.
- W2013672381 creator A5006607584 @default.
- W2013672381 creator A5024617042 @default.
- W2013672381 creator A5057985257 @default.
- W2013672381 creator A5062580306 @default.
- W2013672381 date "2004-12-01" @default.
- W2013672381 modified "2023-09-23" @default.
- W2013672381 title "Tonsillectomy, high dose immunoglobulins, and cyclophosphamide in progressive IgA-nephropathy" @default.
- W2013672381 cites W1969130417 @default.
- W2013672381 cites W1971947423 @default.
- W2013672381 cites W1975362922 @default.
- W2013672381 cites W1984040972 @default.
- W2013672381 cites W1991027093 @default.
- W2013672381 cites W1997906928 @default.
- W2013672381 cites W2001045877 @default.
- W2013672381 cites W2040176121 @default.
- W2013672381 cites W2042965073 @default.
- W2013672381 cites W2105803357 @default.
- W2013672381 cites W2125785855 @default.
- W2013672381 cites W2157306342 @default.
- W2013672381 cites W2168871627 @default.
- W2013672381 doi "https://doi.org/10.1080/03655230410003305" @default.
- W2013672381 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15768795" @default.
- W2013672381 hasPublicationYear "2004" @default.
- W2013672381 type Work @default.
- W2013672381 sameAs 2013672381 @default.
- W2013672381 citedByCount "5" @default.
- W2013672381 countsByYear W20136723812013 @default.
- W2013672381 countsByYear W20136723812016 @default.
- W2013672381 countsByYear W20136723812022 @default.
- W2013672381 crossrefType "journal-article" @default.
- W2013672381 hasAuthorship W2013672381A5006607584 @default.
- W2013672381 hasAuthorship W2013672381A5024617042 @default.
- W2013672381 hasAuthorship W2013672381A5057985257 @default.
- W2013672381 hasAuthorship W2013672381A5062580306 @default.
- W2013672381 hasConcept C126322002 @default.
- W2013672381 hasConcept C126894567 @default.
- W2013672381 hasConcept C134018914 @default.
- W2013672381 hasConcept C141071460 @default.
- W2013672381 hasConcept C159641895 @default.
- W2013672381 hasConcept C2776694085 @default.
- W2013672381 hasConcept C2776755627 @default.
- W2013672381 hasConcept C2779073326 @default.
- W2013672381 hasConcept C2779561371 @default.
- W2013672381 hasConcept C2780091579 @default.
- W2013672381 hasConcept C2780306776 @default.
- W2013672381 hasConcept C2781184683 @default.
- W2013672381 hasConcept C50382708 @default.
- W2013672381 hasConcept C555293320 @default.
- W2013672381 hasConcept C71924100 @default.
- W2013672381 hasConcept C90924648 @default.
- W2013672381 hasConceptScore W2013672381C126322002 @default.
- W2013672381 hasConceptScore W2013672381C126894567 @default.
- W2013672381 hasConceptScore W2013672381C134018914 @default.
- W2013672381 hasConceptScore W2013672381C141071460 @default.
- W2013672381 hasConceptScore W2013672381C159641895 @default.
- W2013672381 hasConceptScore W2013672381C2776694085 @default.
- W2013672381 hasConceptScore W2013672381C2776755627 @default.
- W2013672381 hasConceptScore W2013672381C2779073326 @default.
- W2013672381 hasConceptScore W2013672381C2779561371 @default.
- W2013672381 hasConceptScore W2013672381C2780091579 @default.
- W2013672381 hasConceptScore W2013672381C2780306776 @default.
- W2013672381 hasConceptScore W2013672381C2781184683 @default.
- W2013672381 hasConceptScore W2013672381C50382708 @default.
- W2013672381 hasConceptScore W2013672381C555293320 @default.
- W2013672381 hasConceptScore W2013672381C71924100 @default.
- W2013672381 hasConceptScore W2013672381C90924648 @default.
- W2013672381 hasIssue "sup555" @default.
- W2013672381 hasLocation W20136723811 @default.
- W2013672381 hasLocation W20136723812 @default.
- W2013672381 hasOpenAccess W2013672381 @default.
- W2013672381 hasPrimaryLocation W20136723811 @default.
- W2013672381 hasRelatedWork W1536513376 @default.
- W2013672381 hasRelatedWork W2013672381 @default.
- W2013672381 hasRelatedWork W2013701055 @default.
- W2013672381 hasRelatedWork W2031694281 @default.
- W2013672381 hasRelatedWork W2057561566 @default.
- W2013672381 hasRelatedWork W2067661072 @default.
- W2013672381 hasRelatedWork W2800811471 @default.
- W2013672381 hasRelatedWork W2916219914 @default.
- W2013672381 hasRelatedWork W4235119269 @default.
- W2013672381 hasRelatedWork W593504957 @default.
- W2013672381 hasVolume "124" @default.
- W2013672381 isParatext "false" @default.
- W2013672381 isRetracted "false" @default.
- W2013672381 magId "2013672381" @default.
- W2013672381 workType "article" @default.