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• W2013698997 abstract "Dietary isoflavone intake has been linked to cancer prevention and their anti-inflammation activity was examined. Intraperitoneal lipopolysaccharide (LPS) injection in mice led to a decrease in the liver antioxidant glutathione level but this decrease was prevented in mice fed with an isoflavone-containing diet. Similarly, isoflavone diet prevented the inflammation-associated induction of metallothionein (MT) in the intestine; and the induction of manganese superoxide dismutase (Mn-SOD) in the liver. Results from the intestinal cell studies suggest that isoflavones suppress the intestinal response to inflammation by modulating the action of pro-inflammatory cytokine, IL-6. IL-6 secretion and the STAT3 (signal transducer and activator of transcription protein 3) nuclear translocation in response to IL-6 were both decreased by genistein." @default.
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• W2013698997 date "2004-11-01" @default.
• W2013698997 modified "2023-10-16" @default.
• W2013698997 title "Dietary isoflavones suppress endotoxin-induced inflammatory reaction in liver and intestine" @default.
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• W2013698997 doi "https://doi.org/10.1016/j.canlet.2004.05.019" @default.
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