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- W2013706358 abstract "Carbonic anhydrase was treated with neutral (pH 7) aspirin solutions and also with solutions of aspirin and other acids of pH 3–5. In subsequent enzyme activity determinations no inhibition by the neutral solutions could be demonstrated, whereas the more acid solutions caused a progressive loss of activity with decreasing pH. This effect appeared to be non-specific with respect to the acid used and to depend only upon the hydrogen ion concentration of the carbonic anhydrase solution. The results obtained provide no support for the suggestion that inhibition of carbonic anhydrase may be a factor in aspirin-induced erosion of gastric mucosa." @default.
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- W2013706358 title "The effect of acetylsalicylic acid on carbonic anhydrase in vitro" @default.
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- W2013706358 doi "https://doi.org/10.1016/0006-2952(63)90024-8" @default.
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