FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2013731512> ?p ?o ?g. }

• W2013731512 endingPage "114" @default.
• W2013731512 startingPage "108" @default.
• W2013731512 abstract "Reduction in bile flow is a characteristic of cholestasis related to parenteral nutrition. Light exposure of parenteral multivitamin preparations is the major source of peroxides contaminating parenteral nutrition solutions. They may contribute to local oxidative stress. Oxidants are reported to affect transport mechanisms across the hepatocyte membrane into bile. The authors hypothesize that an oxidant-antioxidant imbalance is involved in parenteral nutrition related cholestasis. The aim of this study was to investigate the roles of multivitamin preparations and peroxides on bile flow in newborn guinea pigs receiving parenteral nutrition.Three-day-old guinea pigs were fed enterally or parenterally with solutions containing 8% dextrose/0.45% NaCl +/- multivitamin preparation +/- amino acids +/- lipids. The influence of the oxidant-antioxidant balance on bile flow was evaluated using 500 microM hydrogen peroxide and 1% and 3% multivitamin preparations +/- Na metabisulfite. Four days later, animals were anesthetized and bile flow was recorded over 2 hours. Glutathione determinations were performed on bile and liver samples. The percentage of oxidized glutathione, reflecting the redox status, was used as a marker of oxidative stress. Data were compared by analysis of variance with P < 0.05.Bile flow decreased first on initiating dextrose + NaCl infusion (a 25% decrease) and subsequently by adding amino acids (a further 30% decrease). Although antioxidant vitamins and peroxides modified the hepatic redox status, they did not influence bile flow.Although the composition of parenteral nutrition affects bile flow and the hepatic redox status, the oxidant-antioxidant imbalance in infused solutions is not the causal event in the installation of cholestasis." @default.
• W2013731512 created "2016-06-24" @default.
• W2013731512 creator A5012183033 @default.
• W2013731512 creator A5019974475 @default.
• W2013731512 creator A5023281427 @default.
• W2013731512 creator A5023988953 @default.
• W2013731512 creator A5039693167 @default.
• W2013731512 creator A5065867902 @default.
• W2013731512 creator A5072619289 @default.
• W2013731512 date "2005-07-01" @default.
• W2013731512 modified "2023-10-04" @default.
• W2013731512 title "Reduced Bile Flow Associated With Parenteral Nutrition Is Independent of Oxidant Load and Parenteral Multivitamins" @default.
• W2013731512 cites W107678392 @default.
• W2013731512 cites W1488294685 @default.
• W2013731512 cites W1573015249 @default.
• W2013731512 cites W1696973241 @default.
• W2013731512 cites W1746645529 @default.
• W2013731512 cites W1893088152 @default.
• W2013731512 cites W1895837554 @default.
• W2013731512 cites W1968672981 @default.
• W2013731512 cites W1973622168 @default.
• W2013731512 cites W1974015135 @default.
• W2013731512 cites W1980493539 @default.
• W2013731512 cites W1982600020 @default.
• W2013731512 cites W1985768301 @default.
• W2013731512 cites W1986102788 @default.
• W2013731512 cites W1986898011 @default.
• W2013731512 cites W1990900224 @default.
• W2013731512 cites W1995499057 @default.
• W2013731512 cites W1996762469 @default.
• W2013731512 cites W2000209160 @default.
• W2013731512 cites W2006258400 @default.
• W2013731512 cites W2006565335 @default.
• W2013731512 cites W2008693141 @default.
• W2013731512 cites W2016880832 @default.
• W2013731512 cites W2018816471 @default.
• W2013731512 cites W2020237295 @default.
• W2013731512 cites W2026051038 @default.
• W2013731512 cites W2028360261 @default.
• W2013731512 cites W2032303808 @default.
• W2013731512 cites W2033564977 @default.
• W2013731512 cites W2037729489 @default.
• W2013731512 cites W2041165219 @default.
• W2013731512 cites W2042119587 @default.
• W2013731512 cites W2044884021 @default.
• W2013731512 cites W2045756227 @default.
• W2013731512 cites W2047601913 @default.
• W2013731512 cites W2048382631 @default.
• W2013731512 cites W2054759094 @default.
• W2013731512 cites W2056886685 @default.
• W2013731512 cites W2059329002 @default.
• W2013731512 cites W2081579636 @default.
• W2013731512 cites W2082069717 @default.
• W2013731512 cites W2083714667 @default.
• W2013731512 cites W2083921892 @default.
• W2013731512 cites W2085556972 @default.
• W2013731512 cites W2087784879 @default.
• W2013731512 cites W2088671412 @default.
• W2013731512 cites W2088822045 @default.
• W2013731512 cites W2088982712 @default.
• W2013731512 cites W2098851662 @default.
• W2013731512 cites W2103101606 @default.
• W2013731512 cites W2104145571 @default.
• W2013731512 cites W2106520238 @default.
• W2013731512 cites W2112308671 @default.
• W2013731512 cites W2112918996 @default.
• W2013731512 cites W2116890047 @default.
• W2013731512 cites W2122040866 @default.
• W2013731512 cites W2128744437 @default.
• W2013731512 cites W2133580717 @default.
• W2013731512 cites W2136792723 @default.
• W2013731512 cites W2136931802 @default.
• W2013731512 cites W2143682660 @default.
• W2013731512 cites W2147891343 @default.
• W2013731512 cites W2152041914 @default.
• W2013731512 cites W2154406430 @default.
• W2013731512 cites W2158564386 @default.
• W2013731512 cites W2159234667 @default.
• W2013731512 cites W2159886668 @default.
• W2013731512 cites W2161620178 @default.
• W2013731512 cites W3146008349 @default.
• W2013731512 cites W4246432676 @default.
• W2013731512 doi "https://doi.org/10.1097/01.wno.0000161661.29391.0d" @default.
• W2013731512 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15990639" @default.
• W2013731512 hasPublicationYear "2005" @default.
• W2013731512 type Work @default.
• W2013731512 sameAs 2013731512 @default.
• W2013731512 citedByCount "38" @default.
• W2013731512 countsByYear W20137315122012 @default.
• W2013731512 countsByYear W20137315122013 @default.
• W2013731512 countsByYear W20137315122014 @default.
• W2013731512 countsByYear W20137315122015 @default.
• W2013731512 countsByYear W20137315122017 @default.
• W2013731512 countsByYear W20137315122018 @default.
• W2013731512 countsByYear W20137315122019 @default.
• W2013731512 countsByYear W20137315122021 @default.
• W2013731512 countsByYear W20137315122022 @default.
• W2013731512 crossrefType "journal-article" @default.

• next