FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2013732013> ?p ?o ?g. }

• W2013732013 endingPage "953" @default.
• W2013732013 startingPage "946" @default.
• W2013732013 abstract "The objective of the study was to investigate the effect of long-term (3.2 years) weight loss on serum levels of the nontraditional cardiovascular risk factors interleukin (IL)-18 and matrix metalloproteinase (MMP)-9. Moreover, we wanted to assess the significance of the magnitude of the weight loss and evaluate the potential effects of 36 months of treatment with the lipase inhibitor orlistat on these parameters. Sixty-eight abdominally obese subjects completed 8 weeks of very low energy diet (600-800 kcal/d) followed by 36 months of randomized treatment with either orlistat or placebo together with lifestyle intervention. Serum levels of IL-18, MMP-9, and leptin were measured by flowmetric xMAP technology (Luminex, Austin, TX). Changes in the levels of IL-18, MMP-9, and leptin were similar in the orlistat and the placebo group during this study. Thus, the 2 groups were combined for further analysis. A weight loss of 8.4 +/- 8.8 kg from baseline to 3.2 years was associated with significant decreases in IL-18 (P < .001), MMP-9 (P < .01), and leptin (P < .001). Matrix metalloproteinase-9 was, however, significantly increased after 8 weeks of very low energy diet-induced weight loss (P < .05). The long-term changes in IL-18 were significantly associated with changes in body mass index independent of changes in blood pressure and lipids (P < .05). Levels and changes of IL-18 and MMP-9 were significantly positively associated at 3.2 years (P < .01). Long-term changes in leptin were significantly associated with changes in IL-18 (P < .01) at 3.2 years. Diet-induced long-term weight loss decreased IL-18 and MMP-9. The decrease in IL-18 was associated with changes in body mass index independent of changes in blood pressure and lipids, indicating that even a minor weight reduction (>5%) has beneficial effects on nontraditional cardiovascular risk markers. Orlistat treatment had no independent effects on IL-18, MMP-9, or leptin in the present study." @default.
• W2013732013 created "2016-06-24" @default.
• W2013732013 creator A5009969953 @default.
• W2013732013 creator A5035111372 @default.
• W2013732013 creator A5038022117 @default.
• W2013732013 creator A5073728816 @default.
• W2013732013 creator A5081337637 @default.
• W2013732013 creator A5082545482 @default.
• W2013732013 date "2009-07-01" @default.
• W2013732013 modified "2023-10-18" @default.
• W2013732013 title "Long-term weight loss decreases the nontraditional cardiovascular risk factors interleukin-18 and matrix metalloproteinase–9 in obese subjects" @default.
• W2013732013 cites W1885912605 @default.
• W2013732013 cites W1966151921 @default.
• W2013732013 cites W1966211343 @default.
• W2013732013 cites W1969040344 @default.
• W2013732013 cites W1971534684 @default.
• W2013732013 cites W1977897098 @default.
• W2013732013 cites W1979031127 @default.
• W2013732013 cites W1982081784 @default.
• W2013732013 cites W1983222044 @default.
• W2013732013 cites W1990692512 @default.
• W2013732013 cites W1991079474 @default.
• W2013732013 cites W1991812354 @default.
• W2013732013 cites W1993800499 @default.
• W2013732013 cites W1993959456 @default.
• W2013732013 cites W2009224194 @default.
• W2013732013 cites W2011128327 @default.
• W2013732013 cites W2021890085 @default.
• W2013732013 cites W2027117067 @default.
• W2013732013 cites W2033538734 @default.
• W2013732013 cites W2042339399 @default.
• W2013732013 cites W2050767863 @default.
• W2013732013 cites W2052175763 @default.
• W2013732013 cites W2056883471 @default.
• W2013732013 cites W2060255139 @default.
• W2013732013 cites W2060981388 @default.
• W2013732013 cites W2073129115 @default.
• W2013732013 cites W2080418085 @default.
• W2013732013 cites W2080752708 @default.
• W2013732013 cites W2096850113 @default.
• W2013732013 cites W2098065069 @default.
• W2013732013 cites W2098354367 @default.
• W2013732013 cites W2098444146 @default.
• W2013732013 cites W2099790921 @default.
• W2013732013 cites W2101630029 @default.
• W2013732013 cites W2101835986 @default.
• W2013732013 cites W2102913741 @default.
• W2013732013 cites W2106319388 @default.
• W2013732013 cites W2106834148 @default.
• W2013732013 cites W2120957560 @default.
• W2013732013 cites W2121445706 @default.
• W2013732013 cites W2126470550 @default.
• W2013732013 cites W2139321163 @default.
• W2013732013 cites W2141265091 @default.
• W2013732013 cites W2150637250 @default.
• W2013732013 cites W2155514454 @default.
• W2013732013 cites W2160412430 @default.
• W2013732013 cites W2164280790 @default.
• W2013732013 cites W2270629577 @default.
• W2013732013 cites W34303986 @default.
• W2013732013 cites W4235391466 @default.
• W2013732013 cites W4239865288 @default.
• W2013732013 cites W4256402462 @default.
• W2013732013 doi "https://doi.org/10.1016/j.metabol.2009.02.031" @default.
• W2013732013 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19409578" @default.
• W2013732013 hasPublicationYear "2009" @default.
• W2013732013 type Work @default.
• W2013732013 sameAs 2013732013 @default.
• W2013732013 citedByCount "37" @default.
• W2013732013 countsByYear W20137320132012 @default.
• W2013732013 countsByYear W20137320132013 @default.
• W2013732013 countsByYear W20137320132014 @default.
• W2013732013 countsByYear W20137320132015 @default.
• W2013732013 countsByYear W20137320132016 @default.
• W2013732013 countsByYear W20137320132017 @default.
• W2013732013 countsByYear W20137320132019 @default.
• W2013732013 countsByYear W20137320132020 @default.
• W2013732013 countsByYear W20137320132021 @default.
• W2013732013 countsByYear W20137320132022 @default.
• W2013732013 countsByYear W20137320132023 @default.
• W2013732013 crossrefType "journal-article" @default.
• W2013732013 hasAuthorship W2013732013A5009969953 @default.
• W2013732013 hasAuthorship W2013732013A5035111372 @default.
• W2013732013 hasAuthorship W2013732013A5038022117 @default.
• W2013732013 hasAuthorship W2013732013A5073728816 @default.
• W2013732013 hasAuthorship W2013732013A5081337637 @default.
• W2013732013 hasAuthorship W2013732013A5082545482 @default.
• W2013732013 hasConcept C126322002 @default.
• W2013732013 hasConcept C134018914 @default.
• W2013732013 hasConcept C142724271 @default.
• W2013732013 hasConcept C194832188 @default.
• W2013732013 hasConcept C204787440 @default.
• W2013732013 hasConcept C27081682 @default.
• W2013732013 hasConcept C2780221984 @default.
• W2013732013 hasConcept C2780613262 @default.
• W2013732013 hasConcept C2780780548 @default.
• W2013732013 hasConcept C511355011 @default.
• W2013732013 hasConcept C544821477 @default.

• next